Aldose reductase inhibitor, fidarestat prevents high-fat diet-induced intestinal polyps in ApcMin/+ mice.

CONCLUSION: Our results thus suggest that fidarestat could be used as a potential chemopreventive drug for intestinal cancers due to APC gene mutations.
PMID: 28786349 [PubMed - as supplied by publisher]

Source: Current Cancer Drug Targets - August 8, 2017 Category: Cancer & Oncology Authors: Saxena A, Tammali R, Ramana KV, Srivastava SK Tags: Curr Cancer Drug Targets Source Type: research