The Effects of Aerobic Exercises and 25(OH) D Supplementation on GLP1 and DPP4 Level in Type II Diabetic Patients

Background:The purpose of this study was to investigate the effects of an 8 ‑week aerobic exercise and supplementation of 25(OH)D3 on GLP1 and DDP4 levels in men with type II diabetes.Methods: In this semiexperimental research, among 40–60 ‑year‑old men with type II diabetes who were referred to the diabetic center of Isabn‑E Maryam hospital in Isfahan; of whom, 48 patients were voluntarily accepted and then were randomly divided into 4 groups: aerobic exercise group, aerobic exercise with 25(OH) D supplement group, 25(OH) D sup plement group, and the control group. An aerobic exercise program was conducted for 8 weeks (3 sessions/week, each session 60 to75 min with 60–80% HRmax). The supplement user group received 50,000 units of oral Vitamin D once weekly for 8 weeks. The GLP1, DPP4, and 25(OH) D levels were measured before and after the intervention. At last, the data were statistically analyzed using the ANCOVA andpost hoctest of least signifcant difference.Results:The results of ANCOVA showed a signifcant difference between the GLP1 and DPP4 levels in aerobic exercise with control group while these changes were not statistically signifcant between the 25(OH) D supplement group with control group (P
Source: International Journal of Preventive Medicine - Category: International Medicine & Public Health Source Type: research

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Source: Microvascular Research - Category: Biochemistry Source Type: research
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