Frailty Status in Older Adults Is Related to Alterations in Indoleamine 2,3-Dioxygenase 1 and Guanosine Triphosphate Cyclohydrolase I  Enzymatic Pathways

Frailty is a multidimensional syndrome correlated to the loss of homeostasis and increased vulnerability to stressors, which is associated with increase in the risk of disability, comorbidity, hospitalization, and death in the elderly. It is based on the interplay of physiological, psychological, social, and environmental factors.

Source: Journal of the American Medical Directors Association - August 8, 2017 Category: Health Management Authors: Diego Marcos-P érez, María Sánchez-Flores, Ana Maseda, Laura Lorenzo-López, José C. Millán-Calenti, Barbara Strasser, Johanna M. Gostner, Dietmar Fuchs, Eduardo Pásaro, Vanessa Valdiglesias, Blanca Laffon Tags: Original Study Source Type: research