Log in to search using one of your social media accounts:


Funding for gene therapy to injured peripheral nerves

(University of Plymouth) Scientists from Plymouth University Peninsula Schools of Medicine and Dentistry have received funding from the Northcott Devon Medical Foundation to explore the potential of gene therapy as a way to enhance functional recovery following microsurgery for injured peripheral nerves.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news

Related Links:

CONCLUSIONS: Our data demonstrate that ACS5 can promote the growth and invasion of CRC cells and provide a potential target for CRC gene therapy. PMID: 28808653 [PubMed - in process]
Source: Canadian Journal of Gastroenterology - Category: Gastroenterology Tags: Can J Gastroenterol Hepatol Source Type: research
This article is protected by copyright. All rights reserved.
Source: Parasite Immunology - Category: Parasitology Authors: Tags: Original Paper Source Type: research
One approach to the structural damage that takes place in heart disease is to attempt to spur growth of new blood vessels, to deliver nutrients to heart tissue that is currently poorly supplied. Gene therapy is in principle well suited to this goal, as a range of genes are known to be involved in regulating the processes of blood vessel generation. So far attempts to create a viable treatment haven't gone so well, unfortunately, but here researchers report success in a recent trial. The results seem promising. At the high level, this approach doesn't address the underlying causes of the situation, the various degenerative ...
Source: Fight Aging! - Category: Research Authors: Tags: Daily News Source Type: blogs
Purpose of review:Leber hereditary optic neuropathy (LHON) is the most common primary mitochondrial DNA (mtDNA) genetic disorder in the population. We address the clinical evolution of the disease, the secondary etiological factors that could contribute to visual loss, and the challenging task of developing effective treatments. Recent findings:LHON is characterized by a preclinical phase that reflects retinal ganglion cell (RGC) dysfunction before rapid visual deterioration ensues. Children can present atypically with slowly progressive visual loss or an insidious/subclinical onset that frequently results in considerable...
Source: Current Opinion in Ophthalmology - Category: Opthalmology Tags: OCULAR GENETICS: Edited by Alex V. Levin Source Type: research
I'll start here by pointing out the most useful application for cryopreservation of cells and tissues: it greatly reduces the cost of logistics in transplant medicine. When you need to coordinate people and cells and places on timescales of a few days, weeks, or months, the ability to confidently put the cells into safe storage for short period of time changes the whole tenor of the affair. Just look at the organ transplant field, for example, which is defined by the fact that this storage cannot yet be achieved. Organ transplantation is enormously expensive not just because the donor pool is limited, but also because orga...
Source: Fight Aging! - Category: Research Authors: Tags: Of Interest Source Type: blogs
Source: Expert Opinion on Biological Therapy - Category: Drugs & Pharmacology Authors: Source Type: research
R Gao
Source: Cancer Gene Therapy - Category: Cancer & Oncology Authors: Source Type: research
Source: Eye - Category: Opthalmology Authors: Source Type: research
Cellular senescence is one of the causes of aging: rising numbers of cells fall into a harmful senescent state and then linger there. The activities of these cells directly contribute to loss of tissue function and the progression of many age-related diseases. You might recall last year's investigations into possible cellular senescence in the immune system, focused on macrophages that exhibit some of the markers used to identify senescent cells. Does this mean that part of the macrophage population is in fact senescent in older people, and they would benefit from the removal of those cells, as is the case for other senesc...
Source: Fight Aging! - Category: Research Authors: Tags: Medicine, Biotech, Research Source Type: blogs
Patient genomes are interpretable only in the context of other genomes; however, genome sharing enables discrimination. Thousands of monogenic diseases have yielded definitive genomic diagnoses and potential gene therapy targets. Here we show how to provide such diagnoses while preserving participant privacy through the use of secure multiparty computation. In multiple real scenarios (small patient cohorts, trio analysis, two-hospital collaboration), we used our methods to identify the causal variant and discover previously unrecognized disease genes and variants while keeping up to 99.7% of all participants’ most se...
Source: ScienceNOW - Category: Science Authors: Tags: Genetics, Medicine, Diseases reports Source Type: news
More News: Dentistry | Funding | Gene Therapy | Genetics | International Medicine & Public Health | Schools