Antipsychotic Polypharmacy With Risperidone and Olanzapine Antipsychotic Polypharmacy With Risperidone and Olanzapine
Given high rates of treatment failure for initial therapy of schizophrenia, is combining risperidone and olanzapine an appropriate approach to improve clinical response and limit adverse effects?Medscape Pharmacists
Schizophrenia in children is uncommon but serious. It may affect their thinking and behavior, and requires careful management. Learn about this condition.
This video covers the main symptoms, criteria for diagnosis, possible causes, and treatment of schizophreniaOsmosis
CONCLUSIONS: For Medicaid enrollees with diabetes and schizophrenia, medical home enrollment is generally associated with greater likelihood of receiving guideline-concordant diabetes care. PMID: 28804075 [PubMed - in process]
Authors: Joshi K, Lafeuille MH, Kamstra R, Tiggelaar S, Lefebvre P, Kim E, Yue Y, Tandon N Abstract AIM: Compare medication utilization, costs and healthcare resource use in schizophrenia patients with substance-related disorders initiated on once-monthly paliperidone palmitate (PP1M) or an oral atypical antipsychotic (OAA). MATERIALS &METHODS: Data from six Medicaid states (07/2009-03/2015) were used to compare outcomes between PP1M and OAA patients. RESULTS: PP1M patients had higher 12-month antipsychotic adherence and persistence than OAA patients. PP1M patients had lower medical (mean monthly cost d...
Schizophrenic patients have been associated with cognitive dysfunction including attention and executive functions. “Shiritori” is a very popular word chain game in Japan. This game requires players to generate a word that begins with the last syllable of the preceding word. The present study assessed the difference of hemodynamic changes between schizophrenic patients and healthy controls during a Japanese w ord production task (shiritori) based on a single-event-related design measured by a multi-channel NIRS system.
Schizophrenic patients show cognitive deficits which are evident in EEG measures. Recent studies have suggested that non-linear EEG indexes might more adequately reflect the complex, irregular, nonstationary behavior of neural processes in schizophrenia than more traditional ERP measures (Fernandez et al., 2011). So far, non-linear analyses have mainly been performed to EEGs from patients at rest, whereas differences in complexity might be more evident during task performance. In addition, most studies have explored complexity at a single time scale.
COVER FIGURE The cover image, by Schahram Akbarian et al., is based on the Review Article The Epigenomics of Schizophrenia, in the Mouse, DOI: 10.1002/ajmg.b.32566.
This study aimed to evaluate the stigma and its correlates among patients with severe mental disorders. Patients with diagnosis of schizophrenia (N=707), bipolar disorder (N=344) and recurrent depressive disorder (N=352) currently in clinical remission from 14 participating centres were assessed on Internalised Stigma of Mental Illness Scale (ISMIS). Patients with diagnosis of schizophrenia experienced higher level of alienation, sterotype endorsement, discrimination experience and total stigma when compared to patients with bipolar disorder and recurrent depressive disorder.
This study aimed to examine the association of schizophrenia with HCV using a population-based dataset in Taiwan. There were 6097 patients with schizophrenia and 6097 sex- and age-matched comparison patients without schizophrenia included in this study. We defined the dependent variable of interest as whether or not a patient had received a diagnosis of HCV.
Patients with schizophrenia tend to have deficits in advanced Theory of Mind (ToM). The “Reading the mind in the eyes” test (RMET), the Faux Pas Task, and the Strange Stories are commonly used for assessing advanced ToM. However, most of the psychometric properties of these 3 measures in patients with schizophrenia are unknown. The aims of this study were to validate the psychometr ic properties of the 3 advanced ToM measures in patients with schizophrenia, including: (1) test-retest reliability; (2) random measurement error; (3) practice effect; (4) concurrent validity; and (5) ecological validity.