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Science News » Patient-Derived Support Cells Stunt Mouse Brain Development

Support cells generated from patients with childhood onset schizophrenia stunted neural circuit development when grafted into developing mouse brains.
Source: National Institute of Mental Health - Category: Psychiatry Authors: Source Type: news

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Authors: Beebe L, Smith KD, Oppizzi LM Abstract Medication adherence and community living problems were assessed by a telephone intervention for stable outpatients with schizophrenia spectrum disorders. A majority were white males who lived with family members. We conducted a descriptive analysis of data gathered during weekly calls to 87 participants receiving weekly TIPS for nine months. Analysis included traditional atheoretical content analysis, Pearson correlations, and Chi squares. The following themes emerged: mood disturbances and related symptoms, psychotic symptoms, coping problems, medication adherence, ...
Source: Issues in Mental Health Nursing - Category: Nursing Tags: Issues Ment Health Nurs Source Type: research
A selective estrogen receptor modulator improves outcomes in men and women with schizophrenia when added to treatment with an antipsychotic.Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Psychiatry News Source Type: news
Increasing evidence links the microbiome's composition with several psychiatric and neurological diseases, including autism, schizophrenia, attention deficit hyperactivity disorder, Parkinson's disease, Alzheimer's disease and multiple sclerosis – Mark Greener investigates.
Source: Progress in Neurology and Psychiatry - Category: Neurology Authors: Tags: News review Source Type: research
Relapse prediction in schizophrenia through digital phenotyping: a pilot study, Published online: 22 February 2018; doi:10.1038/s41386-018-0030-zRelapse prediction in schizophrenia through digital phenotyping: a pilot study
Source: Neuropsychopharmacology - Category: Neurology Authors: Source Type: research
AbstractAssertions regarding attempts to link glial and macrostructural brain events with cognitive performance regarding Albert Einstein, are critically reviewed. One basic problem arises from attempting to draw causal relationships regarding complex, delicately interactive functional processes involving finely tuned molecular and connectivity phenomena expressed in cognitive performance, based on highly variable brain structural events of a single, aged, formalin fixed brain. Data weaknesses and logical flaws are considered. In other instances, similar neuroanatomical observations received different interpretations and c...
Source: Anatomy and Embryology - Category: Anatomy Source Type: research
hiPSC-derived neural stem cells from patients with schizophrenia induce an impaired angiogenesis, Published online: 22 February 2018; doi:10.1038/s41398-018-0095-9hiPSC-derived neural stem cells from patients with schizophrenia induce an impaired angiogenesis
Source: Translational Psychiatry - Category: Psychiatry Authors: Source Type: research
Publication date: June 2018 Source:Schizophrenia Research: Cognition, Volume 12 Author(s): Nerisa Banaj, Federica Piras, Fabrizio Piras, Valentina Ciullo, Mariangela Iorio, Claudia Battaglia, Donatella Pantoli, Giuseppe Ducci, Gianfranco Spalletta The brain structural correlates of cognitive and psychopathological symptoms within the active phase in severely psychotic schizophrenic inpatients have been rarely investigated. Twenty-eight inpatients with a DSM-5 diagnosis of Schizophrenia (SZ), admitted for acute psychotic decompensation, were assessed through a comprehensive neuropsychological and psychopathological battery...
Source: Schizophrenia Research: Cognition - Category: Psychiatry Source Type: research
This article is protected by copyright. All rights reserved. This image is associated with Figure 2 in Grieco et al. in this issue. It is an artistic rendition of their image data illustrating enhanced local excitatory inputs to monocularly deprived PV neurons (white circles) with bath applied NRG1. The eye‐like overlay in black conveys that therapeutic intervention of NRG1/ErbB4 signaling can be developed to help treat critical period‐relevant disorders such as amblyopia. The review article of Grieco et al. addresses a novel and critical role of NRG1/ErbB4 in regulation of visual cortical critical period plasticity.
Source: The Journal of Comparative Neurology - Category: Neurology Authors: Tags: Review Source Type: research
(Case Western Reserve University) An international team of researchers led by a Case Western Reserve University School of Medicine scientist has uncovered a novel mechanism in which a protein--neuregulin 3--controls how key neurotransmitters are released in the brain during schizophrenia. The protein is elevated in people with schizophrenia and other severe mental illnesses, but the study is the first to investigate how it causes such severe mental illness.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
All people are rightly concerned over the school and venue shootings in recent times. We want to do something that will reduce or eliminate these tragedies. Similarly, many violent crimes like robbery are committed with guns. Here are a few ideas that together should help reduce these horrors.1. Require gun owners to have gun safes.When someone wants to buy a gun, a proof of ownership of a gun safe large enough to house the gun must be presented, or a new safe must be purchased at the same time. A typical handgun costs about $500, and a rifle can cost from $500 to $1500. Small, portable gun safes could be prohibited, requi...
Source: The Virtual Salt - Category: Neurology Authors: Source Type: blogs
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