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Previous Asthma Exacerbations Predict Future Events in Mild, Moderate Disease

Study authors propose a new asthma patient “phenotype” in which a previous severe event is the sole predictor of another one.
Source: ConsultantLive - Category: Internal Medicine Authors: Tags: Asthma Respiratory Diseases Source Type: news

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This article briefly reviews the impact of severe asthma on QOL and the potential methods to combat this morbidity including the available therapeutic biologics.
Source: World Allergy Organization Journal - Category: Allergy & Immunology Source Type: research
PMID: 28819960 [PubMed - in process]
Source: Polish Heart Journal - Category: Cardiology Authors: Tags: Kardiol Pol Source Type: research
Authors: Drewek R, Mirea L, Touresian P, Adelson PD Abstract OBJECTIVE: To describe and compare the treatment of acute asthma exacerbations in children seen in the emergency department (ED) and admitted to acute care floor in the hospital or intensive care unit (ICU). METHODS: Retrospective chart review of visits for acute exacerbation of asthma treated at Phoenix Children's Hospital between January 1, 2014 and December 31, 2016. RESULTS: A total of 287 asthma exacerbation cases were identified including 106 (37%) ED visits, 134 (47%) hospital floor and 47 (16%) ICU admissions. History of a previous ED visi...
Source: Journal of Asthma - Category: Respiratory Medicine Tags: J Asthma Source Type: research
Lung cancer is one of the most common malignancies and has a low 5-year survival rate. There are no cheap, simple and widely available screening methods for the early diagnostics of lung cancer. The aim of this study was to determine whether analysis of exhaled breath with an artificial olfactory sensor using support vector analysis can differentiate patients with lung cancer from healthy individuals and patients with other lung diseases, regardless of the stage of lung cancer and the most common comorbidities. Patients with histologically or cytologically verified lung cancer, healthy volunteers and patients with ot...
Source: Journal of Breath Research - Category: Respiratory Medicine Authors: Source Type: research
Background: Tobacco smoking affects both the fraction of exhaled nitric oxide (FeNO) and blood eosinophil (B-Eos) count, two clinically useful biomarkers in respiratory disease that represent local and systemic type-2 inflammation, respectively. Objective: We aimed to study the influence of objectively measured smoke exposure on FeNO and B-Eos in a large population of subjects with and without asthma. Methods: We utilized the US National Health and Nutrition Examination Surveys 2007 –2012 and included 10 669 subjects aged 6–80 years: 9869 controls and 800 asthmatics. Controls were defined as having no res...
Source: Journal of Breath Research - Category: Respiratory Medicine Authors: Source Type: research
Nitric oxide (NO) can be used to detect respiratory or ciliary diseases. Fractional exhaled nitric oxide (FeNO) measurement can reflect ongoing eosinophilic airway inflammation and has a diagnostic utility as a test for asthma screening and follow-up while nasal nitric oxide (nNO) is a valuable screening tool for the diagnosis of primary ciliary dyskinesia. The possibility of collecting airway gas samples in an offline manner offers the advantage to extend these measures and improve the screening and management of these diseases, but normal values from healthy children and teens remain sparse. Methods . Samples were ...
Source: Journal of Breath Research - Category: Respiratory Medicine Authors: Source Type: research
Publication date: Available online 20 August 2017 Source:Brain, Behavior, and Immunity Author(s): Melissa A. Rosenkranz, Stephane Esnault, Bradley T. Christian, Gina Crisafi, Lauren K. Gresham, Andrew T. Higgins, Mollie N. Moore, Sarah M. Moore, Helen Y. Weng, Rachel H. Salk, William W. Busse, Richard J. Davidson
Source: Brain, Behavior, and Immunity - Category: Neurology Source Type: research
Conclusion Plasma leptin in individuals with chronic SCI is inversely associated with FEV1, and FVC, independently of SCI level and severity and other covariates. This finding suggests that plasma leptin may contribute to reduced pulmonary function in chronic SCI. Level of Evidence Level II
Source: PMandR - Category: Rehabilitation Source Type: research
BABIES born to obese mothers are 30 per cent more likely to have chest problems associated with asthma in later life, new research shows.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Prospective, non-interventional study of fixed-dose inhaled corticosteroid (ICS)/long-acting beta2-agonist (LABA) combination therapy with fluticasone propionate/formoterol fumarate (FP/FORM) across a spectrum of community-based patients with asthma in a real-life setting.
Source: Respiratory Medicine - Category: Respiratory Medicine Authors: Source Type: research
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