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Increased brain acidity in psychiatric disorders

(Fujita Health University) Decreased brain pH in the patients with schizophrenia and bipolar disorder has been considered to be the result of secondary factors associated with the diseases, such as medication and agonal state. However, the researchers of the present study suggest that decreased brain pH is a primary feature of the diseases themselves, based on the current findings from systematic investigation using five animal models, which are devoid of such secondary factors.
Source: EurekAlert! - Biology - Category: Biology Source Type: news

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All people are rightly concerned over the school and venue shootings in recent times. We want to do something that will reduce or eliminate these tragedies. Similarly, many violent crimes like robbery are committed with guns. Here are a few ideas that together should help reduce these horrors.1. Require gun owners to have gun safes.When someone wants to buy a gun, a proof of ownership of a gun safe large enough to house the gun must be presented, or a new safe must be purchased at the same time. A typical handgun costs about $500, and a rifle can cost from $500 to $1500. Small, portable gun safes could be prohibited, requi...
Source: The Virtual Salt - Category: Neurology Authors: Source Type: blogs
ConclusionsAdjunctive NAC appears to be a safe treatment that has efficacy for schizophrenia, but not for bipolar disorder or MDD. Further higher quality RCTs are warranted to determine the role of adjunctive NAC in the treatment of major psychiatric disorders.
Source: Acta Psychiatrica Scandinavica - Category: Psychiatry Authors: Tags: Meta ‐analysis Source Type: research
We examined these relationships at the 20-year follow-up assessment of a first-admission sample.
Source: Schizophrenia Research - Category: Psychiatry Authors: Source Type: research
In this study 819 subjects with a diagnosis of SZ (n = 250), schizoaffective disorder (SZA) (n = 228) and bipolar I disorder (BD) (n = 341) were included. Patients with history of BizD and with no BizD were compared with respect to socidemographic and clinical variables, and predictors of BizD were explored. Patients with BizD were less educated, less likely to be married, had higher Positive and Negative Syndrome Scale (PANSS) negative scores and lower Young Mania Rating Scale scores. Younger age, SZ and SZA diagnoses, higher PANSS positive scores, presence of reference delusions, tactile and olfactory halluci...
Source: Asian Journal of Psychiatry - Category: Psychiatry Tags: Asian J Psychiatr Source Type: research
CONCLUSIONS: Findings support the feasibility of implementing IMR within ACT teams. Although there were few significant findings, effect sizes on some variables in this small-scale study and the dose-response relationships within ACT+IMR teams suggest this novel approach could be promising for improving recovery for people with serious mental illness. Further large-scale studies utilizing a hybrid effectiveness-implementation design could provide a promising direction in this area. PMID: 29446335 [PubMed - as supplied by publisher]
Source: Psychiatric Services - Category: Psychiatry Tags: Psychiatr Serv Source Type: research
Conclusions:With the new calling from DSM-5, clinicians treating psychiatric patients should view insomnia less as a symptom of their mental illnesses and treat clinical insomnia as a primary disorder. Patients should also be educated on the importance of reporting and treating their sleep complaints. Nonmedical (cognitive and behavioral) interventions for insomnia need to be further explored given their proven clinical effectiveness.Citation:Seow LSE, Verma SK, Mok YM, Kumar S, Chang S, Satghare P, Hombali A, Vaingankar J, Chong SA, Subramaniam M. Evaluating DSM-5 insomnia disorder and the treatment of sleep problems in a...
Source: Journal of Clinical Sleep Medicine : JCSM - Category: Sleep Medicine Source Type: research
Conclusions: Substantial reductions in health services utilization and costs may be realized with improved medication adherence in Medicaid. These benefits begin to accrue at adherence levels below the common 0.80 PDC threshold. Therefore, interventions should focus not just on perfecting moderate adherers, but also on encouraging Medicaid patients with chronic conditions to initiate pharmacotherapy.
Source: Medical Care - Category: Health Management Tags: Original Articles Source Type: research
Authors: Wojdacz R, Święcicki Ł, Antosik-Wójcińska A Abstract Electroconvulsive therapy (ECT) is the treatment method widely used in psychiatric disorders such as depression, bipolar disorder, schizophrenia and schizoaffective disorder. The advantage of ECT is therapeutic response that occurs significantly earlier than during pharmacotherapy. Initially ECTwas used without anesthesia. Then, in the 1950s procedures with general anesthesia were introduced to reduce the complications that may occur during a seizure caused by ECT, such as broken bones, teeth, tendon rupture, muscle damage. Currently, in gener...
Source: Psychiatria Polska - Category: Psychiatry Tags: Psychiatr Pol Source Type: research
In this study, we measured self-reported pain, risk for SZ, and risk for BD.
Source: The Journal of Pain - Category: Materials Science Authors: Source Type: research
I have read Insane Consequences: How the Mental Health Industry Fails the Mentally Ill a couple of times and am still contemplating it. It also inspired me to research further into how we treat the seriously mentally ill in America. In the book, author DJ Jaffe takes on what he calls the “mental health industry,” and I think that is a fair characterization. He is not the only writer to use the phrase, and he confronts that industry with a voice that reminds me of a prosecuting attorney on a mission. Jaffe became involved in the mental health system in the 1980s when his wife’s 18 year old sister, Lynn, ca...
Source: Psych Central - Category: Psychiatry Authors: Tags: Book Reviews Caregivers Disabilities Policy and Advocacy Psychiatry Psychology Schizophrenia Treatment DJ jaffe mental health policy Mental Illness mental illness violence serious mental illness Source Type: news
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