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Increased brain acidity in psychiatric disorders

(Fujita Health University) Decreased brain pH in the patients with schizophrenia and bipolar disorder has been considered to be the result of secondary factors associated with the diseases, such as medication and agonal state. However, the researchers of the present study suggest that decreased brain pH is a primary feature of the diseases themselves, based on the current findings from systematic investigation using five animal models, which are devoid of such secondary factors.
Source: EurekAlert! - Biology - Category: Biology Source Type: news

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There is a growing recognition of the importance of encouraging patients with mental health problems to become more active as an efficacious strategy to reduce the disability-associated burden. The aim of the current study was to investigate if there are differences in quality of life (QoL) outcomes between people with mental health problems that do and do not meet the recommendations of 150minutes per week of physical activity. 109 (36 ♀) Ugandan in- and outpatients (mean age=34.2±10.2 years) (depression=7, bipolar disorder=31, schizophrenia=21, alcohol use disorder=50) completed the Physical Activity Vital Sign ...
Source: Psychiatry Research - Category: Psychiatry Authors: Source Type: research
This study aimed to evaluate the stigma and its correlates among patients with severe mental disorders. Patients with diagnosis of schizophrenia (N=707), bipolar disorder (N=344) and recurrent depressive disorder (N=352) currently in clinical remission from 14 participating centres were assessed on Internalised Stigma of Mental Illness Scale (ISMIS). Patients with diagnosis of schizophrenia experienced higher level of alienation, sterotype endorsement, discrimination experience and total stigma when compared to patients with bipolar disorder and recurrent depressive disorder.
Source: Psychiatry Research - Category: Psychiatry Authors: Source Type: research
Treatments for cognitive and functional impairments associated with severe mental illnesses are urgently needed. We tested a 12-week, manualized, Compensatory Cognitive Training (CCT) intervention targeting prospective memory, attention, learning/memory, and executive functioning in the context of supported employment for people with severe mental illnesses who were seeking work. 153 unemployed, work-seeking outpatients with schizophrenia/schizoaffective disorder (n=58), bipolar disorder (n=37), or major depression (n=58) were randomized to receive supported employment plus CCT or enhanced supported employment, a robust control group.
Source: Schizophrenia Research - Category: Psychiatry Authors: Source Type: research
Although the Positive and Negative Syndrome Scale (PANSS) was developed for use in schizophrenia (SZ), antipsychotic drug trials use the PANSS to measure symptom change also for bipolar (BP) and schizoaffective (SA) disorder, extending beyond its original indications. If the dimensions measured by the PANSS are different across diagnoses, then the same score change for the same drug condition may have different meanings depending on which group is being studied. Here, we evaluated whether the factor structure in the PANSS was consistent across schizophrenia (n = 3647), bipolar disorder (n = 858), and schizoaffective disorder (n = 592).
Source: Psychiatry Research - Category: Psychiatry Authors: Source Type: research
Adjunctive memantine found effective for negative symptoms of schizophrenia Lithium could benefit patients with bipolar disorder and suicidality Study spotlights simultaneous use of antidepressants, benzodiazepines Study of veterans finds risk of dementia in antipsychotic users Prenatal antidepressant use and ADHD risk explained in part by confounding Postmarket safety events more common in psychiatric drug class
Source: The Brown University Psychopharmacology Update - Category: Psychiatry Tags: Research Roundup Source Type: research
Publication date: Available online 10 August 2017 Source:Progress in Neuro-Psychopharmacology and Biological Psychiatry Author(s): P. Chen, J. Chen, K. Huang, W. Ji, T. Wang, T. Li, Y. Wang, H. Wang, L. He, G. Feng, Y. Shi
Source: Progress in Neuro Psychopharmacology and Biological Psychiatry - Category: Psychiatry Source Type: research
CONCLUSIONS: Much can be done to improve attendance in most services. The initiative like QRG significantly has positive results on patient's follow-up. PMID: 28784394 [PubMed - in process]
Source: Asian Journal of Psychiatry - Category: Psychiatry Tags: Asian J Psychiatr Source Type: research
Publication date: Available online 9 August 2017 Source:The Lancet Psychiatry Author(s): Michael Schönenberg, Eva Wiedemann, Alexander Schneidt, Jonathan Scheeff, Alexander Logemann, Philipp M Keune, Martin Hautzinger Background Many studies suggest that electroencephalographic (EEG) neurofeedback might be beneficial in the treatment of attention-deficit hyperactivity disorder (ADHD). However, numbers of well controlled studies are low and neurofeedback techniques are regarded as highly controversial. The present trial examined the efficacy (compared with sham neurofeedback) and efficiency (compared with meta-cogniti...
Source: The Lancet Psychiatry - Category: Psychiatry Source Type: research
(University of California - Berkeley) Each year, some 2 million people with schizophrenia, bipolar disorder and other mental illnesses are arrested for various crimes, inadvertently turning the US correctional system into the nation's primary provider of inpatient psychiatric care. But an eight-year study led by the University of California, Berkeley, offers a solution.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
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Source: World Journal of Biological Psychiatry - Category: Psychiatry Authors: Source Type: research
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