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Increased brain acidity in psychiatric disorders

(Fujita Health University) Decreased brain pH in the patients with schizophrenia and bipolar disorder has been considered to be the result of secondary factors associated with the diseases, such as medication and agonal state. However, the researchers of the present study suggest that decreased brain pH is a primary feature of the diseases themselves, based on the current findings from systematic investigation using five animal models, which are devoid of such secondary factors.
Source: EurekAlert! - Biology - Category: Biology Source Type: news

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Source: Scandinavian Journal of Immunology - Category: Allergy & Immunology Authors: Tags: Regular Article Source Type: research
Most people understand that the role of psychiatric medications is to help alleviate the symptoms associated with different types of mental disorders, such as depression, bipolar disorder, ADHD, schizophrenia, anxiety, and more. Psychiatric medications are an important part of a comprehensive treatment plan for effectively treating people who have a mental health concern or mental illness. It’s good to know what drugs are being most-often prescribed for mental disorders in the U.S. These are the top 25 psychiatric medications by number of U.S. prescriptions dispensed in 2016, according to QuintilesIMS, a global infor...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: General Medications Psychiatry Treatment medications for mental illness Psychiatric Drugs Psychiatric Medications psychiatric meds top psychiatric medications Source Type: blogs
CONCLUSION: These findings demonstrate the impact of symptomatic remission and resilience on HRQOL of both patients suffering from schizophrenia and BD-I and indicate that these factors are especially relevant for HRQOL of patients with BD-I. PMID: 28992535 [PubMed - as supplied by publisher]
Source: Journal of the Association of European Psychiatrists - Category: Psychiatry Tags: Eur Psychiatry Source Type: research
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Source: Transplant International - Category: Transplant Surgery Authors: Tags: Invited Commentary Source Type: research
The psychopathological condition of Robert Schumann has been a prominent object of study in psychiatry since his hospitalization in 1854. Renowned psychiatrists have diagnosed Schumann with syphilis, schizophrenia, and bipolar and personality disorders. Until today, these analyses of his symptomatology have led to contradictory results. Recent discussion has suggested that his hospitalization was due to professional failure and separation wishes on the part of his wife, her family, and her friends. In line with this hypothesis is the opinion that the separation insisted upon by Clara Schumann was reinforced by the economic...
Source: Psychopathology - Category: Psychiatry & Psychology Source Type: research
In this study, we investigated whether BBOX 1 expression was related to psychiatric disorder in an animal model.
Source: Psychiatry Research - Category: Psychiatry Authors: Source Type: research
Publication date: Available online 7 October 2017 Source:Progress in Neuro-Psychopharmacology and Biological Psychiatry Author(s): Ellen S. Ovenden, Nathaniel W. McGregor, Robin A. Emsley, Louise Warnich Antipsychotic response in schizophrenia is a complex, multifactorial trait influenced by pharmacogenetic factors. With genetic studies thus far providing little biological insight or clinical utility, the field of pharmacoepigenomics has emerged to tackle the so-called “missing heritability” of drug response in disease. Research on psychiatric disorders has only recently started to assess the link between epig...
Source: Progress in Neuro Psychopharmacology and Biological Psychiatry - Category: Psychiatry Source Type: research
Publication date: Available online 3 October 2017 Source:Neuroscience & Biobehavioral Reviews Author(s): Jairo V. Pinto, Thiago C. Moulin, Olavo B. Amaral The search for biomarkers has been a leading endeavor in biological psychiatry. To analyze its evolution over the years, we performed a systematic review to evaluate (a) the most studied peripheral molecular markers in major psychiatric disorders, (b) the main features of studies proposing them as biomarkers and (c) whether their patterns of variation are similar across disorders. Of the six molecules most commonly studied as plasmatic markers of schizophrenia, majo...
Source: Neuroscience and Biobehavioral Reviews - Category: Neuroscience Source Type: research
Conclusions Urgent research questions to further clarify the underlying pathophysiological and structural alterations are further outlined to bring this promising technique to the clinic. PMID: 28971725 [PubMed - as supplied by publisher]
Source: The World Journal of Biological Psychiatry - Category: Psychiatry Authors: Tags: World J Biol Psychiatry Source Type: research
Patients with many psychiatric disorders have considerable internalized stigma. The current study intended to examine the level and impact of internalized stigma in patients with bipolar affective disorder (BPAD). 60 patients with BPAD, 33 patients with schizophrenia and 30 patients with anxiety disorders were compared on Internalized Stigma of Mental Illness scale and The Stigma Scale. The patients with BPAD were assessed using Rosenberg Self-Esteem Scale (RSES), Participation scale (PS) and World Health Organization Quality Of Life - Brief Version – Hindi (WHOQOL-bref).
Source: Psychiatry Research - Category: Psychiatry Authors: Source Type: research
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