Developing the Regulatory Utility of the Exposome: Mapping Exposures for Risk Assessment through Lifestage Exposome Snapshots (LEnS)

Conclusions: The LEnS concept is a practical refinement to the exposome that accounts for total exposures during particular windows of susceptibility in target organ systems. Application of the LEnS framework in risk assessment and regulation will improve protection of children’s health by enhancing protection of sensitive developing organ systems that are critical for lifelong health and well-being. https://doi.org/10.1289/EHP1250 Received: 19 October 2016 Revised: 08 March 2017 Accepted: 04 April 2017 Published: 07 August 2017 Please address correspondence to E.M. Faustman, Dept. of Environmental and Occupational Health Sciences, 4225 Roosevelt Way NE, Suite 100, University of Washington, Seattle, WA 98105 USA. Telephone: (206) 685-2269. Email: faustman@u.washington.edu The authors declare they have no actual or potential competing financial interests. Note to readers with disabilities: EHP strives to ensure that all journal content is accessible to all readers. However, some figures and Supplemental Material published in EHP articles may not conform to 508 standards due to the complexity of the information being presented. If you need assistance accessing journal content, please contact ehponline@niehs.nih.gov. Our staff will work with you to assess and meet your accessibility needs within 3 working days. Introduction The development of the concept of the exposome (Wild 2005) has provided the field of environmental health with the...
Source: EHP Research - Category: Environmental Health Authors: Tags: Commentary Source Type: research

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