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Scientists find new way to attack antibiotic-resistant lung infections

Canadian scientists have discovered a possible way to break through the defences of some antibiotic-resistant respiratory infections.
Source: CBC | Health - Category: Consumer Health News Tags: News/Health Source Type: news

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Publication date: Available online 17 December 2017 Source:Environmental Toxicology and Pharmacology Author(s): Sadia Ashraf, Aftab Ahmad Anjum, Ali Ahmad, Sehrish Firyal, Saba Sana, Asma Abdul Latif Salmonellosis is a major food-borne disease worldwide and antimicrobial resistance in Salmonella is a public health problem. Phytochemicals are alternative therapeutics to treat antibiotic resistant Salmonella. Biochemically identified Salmonella enterica of human and poultry origin (n = 10) were confirmed by polymerase chain reaction. Susceptibility to antibiotics was determined by Kirby Bauer disc diffusion method. In-v...
Source: Environmental Toxicology and Pharmacology - Category: Environmental Health Source Type: research
Centers for Disease Control and Prevention. 04/10/2017 This Web page discusses the extent of antibiotic-resistant bacteria in the United States, and details how the Centers for Disease Control and Prevention is working to address the threat in four areas. It provides links to related pages and documents from the federal government. (Text)
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - Category: International Medicine & Public Health Authors: Source Type: news
[Ethiopian Herald] Antibiotic resistance is a growing public health concern worldwide. When a person is infected with an antibiotic-resistant bacterium, it is not only difficult to treat that patient but also the antibiotic-resistant bacterium spreads to other people causing severe health complications.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
Conclusion Although, mecA resistant genes were found only among clinical MRSA, the occurrence of other bi-component leukocidin genes in a large proportion among the isolates from both community and clinical settings is a major concern. The need for effective resistance and virulence factor surveillance, re-enforcement of antibiotic stewardship and good infection control policy, to prevent dissemination of epidemic strains is highlighted.
Source: Microbial Pathogenesis - Category: Infectious Diseases Source Type: research
Publication date: January 2018 Source:Microbial Pathogenesis, Volume 114 Author(s): Rajagopalan Thaya, Baskaralingam Vaseeharan, Jeyachandran Sivakamavalli, Arokiadhas Iswarya, Marimuthu Govindarajan, Naiyf S. Alharbi, Shine Kadaikunnan, Mohammed N. Al-anbr, Jamal M. Khaled, Giovanni Benelli The successful treatment of multi-drug resistant microbial pathogens represents a major challenge for public health management. Here, chitosan-alginate (CS/ALG) microspheres with narrow size distribution were fabricated by ionically cross linking method using Ca2+ ions as agents for polymer solidification. The physicochemical properti...
Source: Microbial Pathogenesis - Category: Infectious Diseases Source Type: research
Molecules, Vol. 22, Pages 2245: Synergy between Ursolic and Oleanolic Acids from Vitellaria paradoxa Leaf Extract and β-Lactams against Methicillin-Resistant Staphylococcus aureus: In Vitro and In Vivo Activity and Underlying Mechanisms Molecules doi: 10.3390/molecules22122245 Authors: Lucy Catteau Nathalie Reichmann Joshua Olson Mariana Pinho Victor Nizet Françoise Van Bambeke Joëlle Quetin-Leclercq Combining antibiotics with resistance reversing agents is a key strategy to overcome bacterial resistance. Upon screening antimicrobial activities of plants used in traditional medicine, we...
Source: Molecules - Category: Chemistry Authors: Tags: Article Source Type: research
Conclusions Very preterm and very-low birth weight infants were identified as having an increased risk for MRSA colonization on meta-analysis. Multifaceted infection prevention strategies should target these high-risk infants to reduce MRSA colonization rates in NICUs.
Source: American Journal of Infection Control - Category: Infectious Diseases Source Type: research
Publication date: 1 December 2017 Source:American Journal of Infection Control, Volume 45, Issue 12 Author(s): Heather M. Gilmartin, Amanda Hessels
Source: American Journal of Infection Control - Category: Infectious Diseases Source Type: research
Authors: Sekita Y, Murakami K, Yumoto H, Hirao K, Amoh T, Fujiwara N, Hirota K, Fujii H, Matsuo T, Miyake Y, Kashiwada Y Abstract Dental biofilms that form in the oral cavity play a critical role in the pathogenesis of several infectious oral diseases, including dental caries, periodontal disease, and oral candidiasis. Houttuynia cordata (HC, Saururaceae) is a widely used traditional medicine, for both internal and external application. A decoction of dried HC leaves (dHC) has long been consumed as a health-promoting herbal tea in Japan. We have recently reported that a water solution of HC poultice ethanol extract...
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
Conclusion: Lysostaphin causes rapid lysis of S. aureus. Combination therapies that include linezolid and lysostaphin could be used in life-threatening infections, such as endocarditis to increase the early in vivo activity of the antibiotics, and to prevent the emergence of linezolid resistant mutants. Further, in vivo studies are warranted to confirm our results. PMID: 29238455 [PubMed]
Source: Iranian Journal of Microbiology - Category: Microbiology Tags: Iran J Microbiol Source Type: research
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