Comparison of hybrid 68 Ga-PSMA-PET/CT and 99m Tc-DPD-SPECT/CT for the detection of bone metastases in prostate cancer patients: Additional value of morphologic information from low dose CT

Conclusion68Ga-PSMA-PET outperforms99mTc-DPD-SPECT in detecting bone metastases in PC patients. Additional information from low-dose-CT resulted in a significant reduction in equivocal lesions in both modalities, however68Ga-PSMA-PET benefited most.Key Points•Ga-PSMA-PET outperforms99mTc-DPD-SPECT in skeletal staging in prostate cancer patients•Proportion of equivocal decisions was significantly reduced by CT-fusion in both modalities•Ga-PSMA-PET benefits more from CT information,compared to99mTc-DPD-SPECT
Source: European Radiology - Category: Radiology Source Type: research