Evaluating Random Error in Clinician-Administered Surveys: Theoretical Considerations and Clinical Applications of Interobserver Reliability and Agreement.
Conclusions: This study demonstrates that the methodology used to evaluate survey score concordance can influence the statistical results obtained and thus affect clinical interpretations. PMID: 28768319 [PubMed - as supplied by publisher]
[The Herald] Jibilika Dance Trust, an organisation which promotes the development of urban arts culture among youths in Zimbabwe, has begun its health awareness campaign called "Step Up 2 HIV" for 2018.The campaign promotes dissemination of information on HIV-related issues in form of art conveyed through music and dance and is expected to run until December.
(Columbia University School of Engineering and Applied Science) A team led by Columbia University Biomedical Engineering Professor Gordana Vunjak-Novakovic has designed a creative new approach to help injured hearts regenerate by applying extracellular vesicles secreted by cardiomyocytes rather than implanting the cells. The study shows that the cardiomyocytes derived from human pluripotent stem cells (derived in turn from a small sample of blood) could be a powerful, untapped source of therapeutic microvesicles that could lead to safe and effective treatments of damaged hearts.
We report on a case of plasmablastic lymphoma (PBL) with hemophagocytic lymphohistiocytosis (HLH).A-53-year-old Japanese man was diagnosed with PBL and AIDS. In addition to combined antiretroviral therapy, HyperCVAD (cyclophosphamide, doxorubicin, vincristine, prednisone)/high-dose methotrexate + cytarabine was initiated immediately. Partial remission was attained with chemotherapy. However, the patient developed HLH and died despite intensive therapy. Autopsy findings suggested that PBL was controlled, and immunosuppression appeared to cause fatal infection. The patient showed high titers of EBV viral-capsid antigen (VCA)...
Fibre aids fight against nasty gut infection, Published online: 23 April 2018; doi:10.1038/d41586-018-04957-wWell-nourished microbiome can shut out potentially lethal bacteria.
DISCUSSION: We estimated that 10,110 PLHIV resided in NSW in 2016 (range 8400 to 11,720), among whom 9230 (91.3%) were diagnosed, and 8490 (92.0% of those diagnosed) were receiving ART. Among PLDHIV receiving ART, 8020 (94.5%) had suppressed viral load (
CONCLUSION: Both community-models had similar population-level effectiveness for rapidly identifying people living with HIV but differed in effectively transitioning them to treatment. Comprehensiveness, integration and attention to barriers to care are important in the design of community antiretroviral treatment delivery. PMID: 29675995 [PubMed - in process]
Publication date: Available online 21 April 2018 Source:Global Heart Author(s): Christopher T. Longenecker, Ankur Kalra, Emmy Okello, Peter Lwabi, John O. Omagino, Cissy Kityo, Moses R. Kamya, Allison R. Webel, Daniel I. Simon, Robert A. Salata, Marco A. Costa In this case study, we describe an ongoing approach to develop sustainable acute and chronic cardiovascular care infrastructure in Uganda that involves patient and provider participation. Leveraging strong infrastructure for HIV/AIDS care delivery, University Hospitals Harrington Heart and Vascular Institute and Case Western Reserve University have partnered with U....
[Observer] The government has revived its HIV testing guidelines of 2016 and started encouraging all family members with HIV positive patients to be screened.
This study adds to our understanding of stigma by assessing how perceived stigma varies from one context to another and how such differences are associated with the location where individuals would prefer an HIV test. We used self-administered questionnaire data (n = 378) obtained from a convenience sample of students (18 years and older) attending a tertiary education institution in Durban, South Africa. Perceived stigma in the university environment was compared to perceived stigma in the home community environment. Multiple logistic regression analysis tested whether a higher level of perceived stigma in one setting was...