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Change in Conversion Definition May Improve TB Detection

Increase from IFN γ0.7 IU/mL would improve identification of those at risk of tuberculosis
Source: Pulmonary Medicine News - Doctors Lounge - Category: Respiratory Medicine Tags: Infections, Pulmonology, Journal, Source Type: news

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Alexander V. Panteleev, Irina Yu Nikitina, Irina A. Burmistrova, George A. Kosmiadi, Tatyana V. Radaeva, Rasul B. Amansahedov, Pavel V. Sadikov, Yana V. Serdyuk, Elena E. Larionova, Tatef R. Bagdasarian, Larisa N. Chernousova, Vitaly V. Ganusov, Irina V. Lyadova
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
Conclusion The static TD measured at RV and at TLC are preserved in COPD. The TF bilaterally was significantly decreased in COPD group and is decreased with increasing severity of COPD. The negative correlation of TF and PaCO2 indicates that the diaphragm dysfunction is the main contributor to neuromuscular respiratory failure in COPD patients.
Source: Egyptian Journal of Chest Diseases and Tuberculosis - Category: Respiratory Medicine Source Type: research
ConclusionThe pooled prevalence of tuberculosis among prisoners in Ethiopia is expectedly high. This high prevalence could explain the spread of TB within prisons and between prisoners and varies communities. Thus; attention should be given to prison settings to prevent the transmission and emergence of drug resistance TB both in inmates and general population. Further studies covering large scale prison population are needed to design effective diagnostic, treatment and preventive methods.
Source: Archives of Public Health - Category: International Medicine & Public Health Source Type: research
Publication date: Available online 19 August 2017 Source:Veterinary Microbiology Author(s): Jobin Thomas, María Ángeles Risalde, Miriam Serrano, Iker Sevilla, Mariví Geijo, José Antonio Ortíz, Miguel Fuertes, José Francisco Ruíz-Fons, José de la Fuente, Lucas Domínguez, Ramón Juste, Joseba Garrido, Christian Gortázar Deer species (family Cervidae) are often part of the Mycobacterium tuberculosis complex maintenance host community, and tuberculosis (TB) control in deer, including vaccination, is consequently an area of ongoing research. However, m...
Source: Veterinary Microbiology - Category: Veterinary Research Source Type: research
Conclusions: Stool Xpert can rapidly confirm TB in children who present with radiologic findings suggestive of severe TB. In resource-limited settings where children frequently present with advanced disease, Xpert on stool samples could improve access to rapid diagnostic confirmation and appropriate treatment.
Source: The Pediatric Infectious Disease Journal - Category: Infectious Diseases Tags: Original Studies Source Type: research
AbstractBovine tuberculosis (bovine TB) is a controversial animal health policy issue in England, which impacts farmers, the public, cattle and badgers. Badgers (Meles meles) act as a wildlife reservoir of disease. Policy options for badger control include (1) do nothing, (2) badger culling, and (3) badger vaccination. This paper argues for mandatory Animal Welfare Impact Assessment (AWIA) for all policy that significantly affects sentient animals. AWIA includes (1) species description, and (2) AWIA analysis stages. In this paper, AWIA is applied to impacts of bovine TB policy options on cattle and badgers. Over 4  ye...
Source: Journal of Agricultural and Environmental Ethics - Category: Medical Ethics Source Type: research
In this study, zebrafish was employed as the infection model to explore the pathogenesis of SVCV. 4 groups of zebrafish tissues were set and RNA sequencing (RNA-Seq) technology was employed to analyze the differentially expressed genes (DEGs) after SVCV-infection. A total of 360,971,498 clean reads were obtained from 12 samples, 382 DEGs in the brain and 926 DEGs in the spleen were identified. These DEGs were annotated into three ontologies after gene ontology (GO) enrichment analysis. The Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis showed that these DEGs were primarily related to Influenza A pathway an...
Source: Fish and Shellfish Immunology - Category: Biology Source Type: research
The Bacillus Calmette –Guérin (BCG) vaccine protects against disseminated tuberculosis (TB) and TB meningitis and is one of the most widely used vaccines worldwide. BCG has been included in the national immunization program in Taiwan since 1965.1 Since then, healthy neonates in Taiwan were immunized 24 h after birth with the Tokyo-172–based BCG vaccine until 2016, when the recommended BCG immunization timing was changed to 5–8 months of age.
Source: Pediatrics and Neonatology - Category: Perinatology & Neonatology Authors: Tags: Short Communication Source Type: research
Managing a difficult airway in pregnancy is a challenging procedure for an anesthesiologist. Over the course of pregnancy, Mallampati score worsens in association with fluid retention,[1] and contributes to the increased risk of failed intubation in the pregnant compared to the general surgical population.[2,3] The pregnant patient is also at greater risk of aspiration, making the consequences of failed intubation more severe.
Source: International Journal of Obstetric Anesthesia - Category: Anesthesiology Authors: Source Type: research
CONCLUSIONS: Cough was the commonest finding among these MDRTB patients, with 179 (92.75%) of them presenting with cough, followed by chest X-ray consolidation in 156 patients (80.83%) and history of previous TB treatment in 151 patients (78.24%). Cigarette smoking, HIV positivity, and low CD4 counts were significantly associated with MDRTB mortality, p values of 0.034, 0.044, and 0.048, respectively. Fever on the other hand was at the borderline with p value of 0.059. We conclude that cigarette smoking and HIV status are significant risk factors for mortality among MDRTB patients. HIV screening should continually be empha...
Source: Journal of Tropical Medicine - Category: Tropical Medicine Tags: J Trop Med Source Type: research
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