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Change in Conversion Definition May Improve TB Detection

Increase from IFN γ0.7 IU/mL would improve identification of those at risk of tuberculosis
Source: Pulmonary Medicine News - Doctors Lounge - Category: Respiratory Medicine Tags: Infections, Pulmonology, Journal, Source Type: news

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CONCLUSIONS: In this paper, we describe the importance and implementation of USFDA's tentative approval process to review ARVs for resource-constrained settings. We also highlight the impact of patents and exclusivities on review of HIV drugs under tFDA and illustrate the concepts using a new HIV drug as an example. PMID: 29232052 [PubMed - in process]
Source: Journal of the International AIDS Society - Category: Infectious Diseases Tags: J Int AIDS Soc Source Type: research
Source: CDC Morbidity and Mortality Weekly Report - Category: American Health Source Type: news
CONCLUSION: The tubercular hypophysitis, as a result of performed tests, is discussed hereby, in the case report. PMID: 29232189 [PubMed - in process]
Source: Endocrine Regulations - Category: Endocrinology Tags: Endocr Regul Source Type: research
We report a case of HIV-associated opsoclonus-myoclonus and early HIV infection. A review of published literature shows opsoclonus-myoclonus can occur during early infection, in immune reconstitution syndrome or in association with other infections, especially tuberculosis.
Source: Journal of NeuroVirology - Category: Neurology Source Type: research
For the first time, a urine test has been developed that reliably detects tuberculosis – a valuable weapon in the fight against an infection that kills millions
Source: New Scientist - Health - Category: Consumer Health News Source Type: research
European Union, European Centre for Disease Prevention and Control. 11/13/2017 This 228-page report presents the results of the zoonoses monitoring activities carried out in 2016 in 37 European countries (28 Member States [MS] and nine non-MS). It summarizes trends and sources for Yersinia (plague) and tularemia, both Category A bioterrorism agents; brucella, a Category B bioterrorism Agent; bovine tuberculosis, trichinellosis, echinococcosis, toxoplasmosis, rabies, Q fever, and West Nile fever. (PDF)
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - Category: International Medicine & Public Health Authors: Source Type: news
Abstract Protein-protein interaction (PPI) network analysis is a powerful strategy to understand M. tuberculosis (Mtb) system level physiology in the identification of hub proteins. In the present study, the PPI network of 79 Mtb toxin-antitoxin (TA) systems comprising of 167 nodes and 234 edges was investigated. The topological properties of PPI network were examined by 'Network analyzer' a cytoscape plugin app and STRING database. The key enriched biological processes and the molecular functions of Mtb TA systems were analyzed by STRING. Manual curation of the PPI data identified four proteins (i.e. Rv2762c, Vap...
Source: Bioinformation - Category: Bioinformatics Authors: Tags: Bioinformation Source Type: research
Authors: Khan N, Vidyarthi A, Pahari S, Agrewala JN Abstract Dendritic cells (DCs) and macrophages (Mϕs) are professional antigen-presenting cells (APCs) that can efficiently phagocytose Mycobacterium tuberculosis (Mtb), the etiological agent of tuberculosis (TB). It is quite interesting to mention here that DCs and Mϕs use distinct strategies to combat and eliminate Mtb. Similarly, Mtb employs different mechanisms to counteract the action of DCs and Mϕs. Mϕs are evolved with specialized, innate, defensive machinery to restrict growth of Mtb at the initial phase of infection. However, DCs are more endowed towar...
Source: International Reviews of Immunology - Category: Allergy & Immunology Tags: Int Rev Immunol Source Type: research
(American Association for the Advancement of Science) Scientists have finally developed a noninvasive tuberculosis test for a pool of people for whom such assessments have previously been difficult: people who don't have HIV.
Source: EurekAlert! - Infectious and Emerging Diseases - Category: Infectious Diseases Source Type: news
Authors: Kim CH, Kim EJ, Cha SI, Lee J PMID: 29225259 [PubMed - as supplied by publisher]
Source: Internal Medicine - Category: Internal Medicine Tags: Intern Med Source Type: research
More News: Respiratory Medicine | Tuberculosis