Brain molecular changes and behavioral alterations induced by propofol anesthesia exposure in peripubertal rats

ConclusionIn peripubertal rats, propofol anesthesia exposure induces transient molecular and behavioral response that share similarities with those reported previously for addictive drugs. In the absence of additional pharmacological manipulation, all detected effects receded within 48 hour after the treatment.

Source: Pediatric Anesthesia - August 3, 2017 Category: Anesthesiology Authors: Željko Pavković, Kosara Smiljanić, Selma Kanazir, Desanka Milanović, Vesna Pešić, Sabera Ruždijić Tags: RESEARCH REPORT Source Type: research