Tumor ‐associated microglia/macrophages predict poor prognosis in high‐grade gliomas and correlate with an aggressive tumor subtype

ConclusionsThis is the first study to use automated quantitative immunofluorescence to determine the prognostic impact of TAMs. Our results suggest that M2‐like TAMs hold an unfavorable prognostic value in high‐grade gliomas and may contribute to a protumorigenic microenvironment.This article is protected by copyright. All rights reserved.

Source: Neuropathology and Applied Neurobiology - August 1, 2017 Category: Neurology Authors: Mia D. S ørensen, Rikke H. Dahlrot, Henning B. Boldt, Steinbjørn Hansen, Bjarne W. Kristensen Tags: Original Article Source Type: research