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A medical student is diagnosed with cancer. Here is his story.

I began medical school, like many of my peers, with some experience working with patients. I worked as a volunteer EMT with Cornell University EMS for four years during my undergraduate years; shadowed a cardiologist and an anesthesiologist through Cornell’s Urban Summer program at NYP Hospital–Cornell and worked with patients during Global Medical Brigade trips to rural Honduras. All of this sparked my interest in medicine, but to claim I had any real understanding of a patient’s existential journey through serious disease would be an overstatement. That changed abruptly at the start of my first year at Albert Einstein College of Medicine, when, after all the years of hard work to begin my dream of becoming a physician, I was blindsided by an unimaginable role reversal. Halfway through my clinical anatomy course, as I was learning the beautifully complex organization of the human body, I noticed a small lump at the base of my neck. Fast-forward two weeks: There was a series of doctor visits, scans, discrepancies in the diagnosis, nail-biting waits for biopsies and even a scheduled — then cancelled — major surgery. Finally, I received the conclusive biopsy result. The diagnosis: primary mediastinal B-cell lymphoma. Continue reading ... Your patients are rating you online: How to respond. Manage your online reputation: A social media guide. Find out how.
Source: Kevin, M.D. - Medical Weblog - Category: General Medicine Authors: Tags: Conditions Cancer Medical school Source Type: blogs

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NCI ’ s Center for Cancer Research (CCR) Grand Rounds Dr. Ali Shilatifard, Professor and Chairman of the Department of Biochemistry and Molecular Genetics of the Northwestern University Feinberg School of Medicine, is a world renown biochemist and molecular biologist. He is a respected expert in the field of transcription and epigenetics, specifically as it relates to cancer biology. He has an immense interest in understanding the intricate molecular mechanisms of the regulation of gene expression, the mechanisms that activate or suppress a particular gene ’ s traits. As a Jane Coffin Childs postdoctoral fellow...
Source: Videocast - All Events - Category: General Medicine Tags: Upcoming Events Source Type: video
Conditions:   Non-Hodgkin's Lymphoma;   Multiple Myeloma Interventions:   Procedure: Hematopoietic Cell Transplantation;   Drug: Tbo-filgrastim Sponsor:   Sidney Kimmel Cancer Center at Thomas Jefferson University Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
A second version of a new cancer treatment that uses a patient's own cells to fight non-Hodgkin's lymphoma has been approved by the FDA. Now 15,000 people may be eligible for the treatment. Dr. Tara Narula reports.
Source: Health News: CBSNews.com - Category: Consumer Health News Source Type: news
Members of the B-cell lymphoma 2 (BCL-2) gene family are attractive targets for cancer therapy as they play a key role in promoting cell survival, a long-since established hallmark of cancer. Clinical utility for selective inhibition of specific anti-apoptotic Bcl-2 family proteins has recently been realized with the Food and Drug Administration (FDA) approval of venetoclax (formerly ABT-199/GDC-0199) in relapsed chronic lymphocytic leukemia (CLL) with 17p deletion. Despite the impressive monotherapy activity in CLL, such responses have rarely been observed in other B-cell malignancies, and preclinical data suggest that co...
Source: Biochemical Journal - Category: Biochemistry Authors: Tags: Review Articles Source Type: research
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Source: Cancer Science - Category: Cancer & Oncology Authors: Tags: Original Article Source Type: research
Authors: Ji Y, Lu H Abstract Currently, HIV infection and AIDS are still one of the most important epidemic diseases around the world. As early in the initial stage of HIV epidemic, the high incidence of ADCs including Kaposi sarcoma and non-Hodgkin's lymphoma was the substantial amount of disease burden of HIV infection and AIDS. With the increasing accessibility of HAART and improving medical care for HIV infection and AIDS, AIDS-related illness including ADCs has dramatically decreased. Meanwhile, the incidence of NADCs rises in PLWH. Compared with the general population, most of cancers are more likely to attac...
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
Authors: Yi Z, Yuan Z Abstract Most hepatitis C virus (HCV) infection results in persistent infection. Significant portion of chronic HCV-infected patients develop hepatocellular carcinoma (HCC). Chronic hepatitis C is also associated with extrahepatic manifestations, including cryoglobulinemia, lymphoma, insulin resistance, type 2 diabetes, and neurological disorders. The molecular mechanisms of how HCV infection causes liver cancer are largely unknown. HCV replication or viral proteins may perturb cellular hemostasis and induce the generation of reactive oxygen species (ROS); viral components or viral replication...
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
Authors: Pei Y, Lewis AE, Robertson ES Abstract Epstein-Barr virus (EBV) was the first human tumor virus discovered more than 50 years ago. EBV-associated lymphomagenesis is still a significant viral-associated disease as it involves a diverse range of pathologies, especially B-cell lymphomas. Recent development of high-throughput next-generation sequencing technologies and in vivo mouse models have significantly promoted our understanding of the fundamental molecular mechanisms which drive these cancers and allowed for the development of therapeutic intervention strategies. This review will highlight the curr...
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
Authors: MacDonald M, You J Abstract Merkel cell polyomavirus (MCPyV or MCV) is a novel human polyomavirus that has been discovered in Merkel cell carcinoma (MCC), a highly aggressive skin cancer. MCPyV infection is widespread in the general population. MCPyV-associated MCC is one of the most aggressive skin cancers, killing more patients than other well-known cancers such as cutaneous T-cell lymphoma and chronic myelogenous leukemia (CML). Currently, however, there is no effective drug for curing this cancer. The incidence of MCC has tripled over the past two decades. With the widespread infection of MCPyV and the...
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
ConclusionsLow quality evidence supports the use of GnRHa before and/or during chemotherapy to reduce the risk of POI and increase the probability of spontaneous pregnancy in the short term. Further high quality RCTs with more accurate assessment of ovarian reserve are needed to support any practical recommendation.
Source: Ultrasound in Obstetrics and Gynecology - Category: Radiology Authors: Tags: Systematic Review Source Type: research
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