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A medical student is diagnosed with cancer. Here is his story.

I began medical school, like many of my peers, with some experience working with patients. I worked as a volunteer EMT with Cornell University EMS for four years during my undergraduate years; shadowed a cardiologist and an anesthesiologist through Cornell’s Urban Summer program at NYP Hospital–Cornell and worked with patients during Global Medical Brigade trips to rural Honduras. All of this sparked my interest in medicine, but to claim I had any real understanding of a patient’s existential journey through serious disease would be an overstatement. That changed abruptly at the start of my first year at Albert Einstein College of Medicine, when, after all the years of hard work to begin my dream of becoming a physician, I was blindsided by an unimaginable role reversal. Halfway through my clinical anatomy course, as I was learning the beautifully complex organization of the human body, I noticed a small lump at the base of my neck. Fast-forward two weeks: There was a series of doctor visits, scans, discrepancies in the diagnosis, nail-biting waits for biopsies and even a scheduled — then cancelled — major surgery. Finally, I received the conclusive biopsy result. The diagnosis: primary mediastinal B-cell lymphoma. Continue reading ... Your patients are rating you online: How to respond. Manage your online reputation: A social media guide. Find out how.
Source: Kevin, M.D. - Medical Weblog - Category: General Medicine Authors: Tags: Conditions Cancer Medical school Source Type: blogs

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This study tells us there are two ways in which a virus, nothing more than a “parasite,” can infect its host cell: 1. actively, by causing “a lytic infection characterized by the release of new progeny virus particles, often upon the lysis of the host cell,” (lysis refers to the destruction of a cell, the host cell in this case), or 2. inactively, which occurs when the virus just sleeps, without reproducing itself. “Reactivation” occurs when a sleeping virus wakes up and reproduces, stimulated by internal or external factors…but that gets into too much detail, so let’s ...
Source: Margaret's Corner - Category: Cancer & Oncology Authors: Tags: Blogroll EBV Epstein-Barr myeloma Source Type: blogs
The risk of developing estrogen-receptor-negative breast cancer following Hodgkin's lymphoma is increased regardless of prior radiotherapy.Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news
Rubinstein–Taybi syndrome (RSTS) is a multiple congenital anomalies syndrome associated with mutations in CREBBP (70%) and EP300 (5–10%). Previous reports have suggested an increased incidence of specific benign and possibly also malignant tumors. We identified all known individuals diagnosed with RSTS in the Netherlands until 2015 (n = 87) and studied the incidence and character of neoplastic tumors in relation to their CREBBP/EP300 alterations. The population–based Dutch RSTS data are compared to similar data of the Dutch general population and to an overview of case reports and series of ...
Source: American Journal of Medical Genetics Part A - Category: Genetics & Stem Cells Authors: Tags: ORIGINAL ARTICLE Source Type: research
In January, 2018, Academic Press published my bookPrecision Medicine and the Reinvention of Human Disease. This book has an excellent " look inside " at itsGoogle book site, which includes the Table of Contents. In addition, I thought it might be helpful to see the topics listed in the Book's index. Note that page numbers followed by f indicate figures, t indicate tables, and ge indicate glossary terms.AAbandonware, 270, 310geAb initio, 34, 48ge, 108geABL (abelson leukemia) gene, 28, 58ge, 95 –97Absidia corymbifera, 218Acanthameoba, 213Acanthosis nigricans, 144geAchondroplasia, 74, 143ge, 354geAcne, 54ge, 1...
Source: Specified Life - Category: Information Technology Tags: index jules berman jules j berman precision medicine Source Type: blogs
Abstract High‐throughput sequencing has significantly contributed to revealing the molecular underpinnings of B‐cell lymphomagenesis and disease progression. It is now a widely accepted concept that the diversity of clinical responses to front‐line therapy and the development of relapsed/refractory disease are in part explained by “interpatient” genetic heterogeneity measurable by individual sets of somatic gene alterations in tumor genomes. Moreover, extensive “intratumor” heterogeneity on the genotypic and phenotypic levels is the product of ongoing tumor evolution and adaptation to various ...
Source: The Journal of Pathology - Category: Pathology Authors: Tags: Invited Review Source Type: research
AbstractPurposePrimary breast lymphoma (PBL) comprises  
Source: Breast Cancer Research and Treatment - Category: Cancer & Oncology Source Type: research
This study updated the temporal trends and variations of MCL incidence in the SEER areas and compared them with counterpart data in Texas. Results: From 1995 to 2013, there were 2, 435 and 5, 193 newly diagnosed MCL patients in Texas and SEER areas. Age-adjusted MCL incidence was 0.91 per 100,000 persons per year in Texas and 1.01 in SEER areas. MCL incidence increased steadily with an annual percent change (APC) of 2.56% in SEER areas and an APC of 2.16% in Texas. In SEER areas, APCs for MCL incidence were significantly different from zero in patients with advanced stage tumor (3.33%), male (2.71%), elderly patients &...
Source: Oncotarget - Category: Cancer & Oncology Tags: Oncotarget Source Type: research
We examined changes in the cluster of differentiation CD44+/CD24−CSC population and behavior using the breast cancer cell line MCF-7. Key findings Our results indicated that cell viability, clone formation, mammosphere generation, and nude mice tumor metastasis were inhibited in the CD44+/CD24− population and that MCF-7 cells exhibited G1-phase arrest after quercetin treatment. Additionally, CyclinD1 and B cell lymphoma-2 expression were suppressed and Bcl-2-like protein-4 expression was enhanced after quercetin treatment. We also observed that estrogen receptor α and phosphatidylinositol-3-kinase (PI3K)/...
Source: Life Sciences - Category: Biology Source Type: research
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Source: American Journal of Hematology - Category: Hematology Authors: Tags: Research Article Source Type: research
It took a team of UCLA medical professionals and the generosity of 71 strangers to save 2-year-old Skye Savren-McCormick ’s life.The toddler from Ventura, California, required frequent blood and platelet transfusions, often on a daily basis, while undergoing  three grueling bone-marrow transplants, surgery to remove her swollen spleen and seven rounds of chemotherapy for leukemia and lymphoma. She received 77 units of blood and platelets during a 10-month stay at UCLA Mattel Children ’s Hospital.  Recently Skye ’s family got to meet and thank two dozen of the 71 strangers whose blood a...
Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news
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