Contributions for classification of platelet rich plasma - proposal of a new classification: MARSPILL.

Contributions for classification of platelet rich plasma - proposal of a new classification: MARSPILL.
Regen Med. 2017 Jul 31;:
Authors: Lana JFSD, Purita J, Paulus C, Huber SC, Rodrigues BL, Rodrigues AA, Santana MH, Madureira JL, Malheiros Luzo ÂC, Belangero WD, Annichino-Bizzacchi JM
Abstract
Platelet-rich plasma (PRP) has emerged as a significant therapy used in medical conditions with heterogeneous results. There are some important classifications to try to standardize the PRP procedure. The aim of this report is to describe PRP contents studying celular and molecular components, and also propose a new classification for PRP. The main focus is on mononuclear cells, which comprise progenitor cells and monocytes. In addition, there are important variables related to PRP application incorporated in this study, which are the harvest method, activation, red blood cells, number of spins, image guidance, leukocytes number and light activation. The other focus is the discussion about progenitor cells presence on peripherial blood which are interesting due to neovasculogenesis and proliferation. The function of monocytes (in tissue-macrophages) are discussed here and also its plasticity, a potential property for regenerative medicine treatments.
PMID: 28758836 [PubMed - as supplied by publisher]

Source: Regenerative Medicine - July 31, 2017 Category: Genetics & Stem Cells Authors: Lana JFSD, Purita J, Paulus C, Huber SC, Rodrigues BL, Rodrigues AA, Santana MH, Madureira JL, Malheiros Luzo ÂC, Belangero WD, Annichino-Bizzacchi JM Tags: Regen Med Source Type: research