Rechargeable microbial anti-adhesive polymethyl methacrylate incorporating silver sulfadiazine-loaded mesoporous silica nanocarriers

Polymethyl methacrylate (PMMA), which has been clinically accepted for over 70 years, has been used as a biomaterial in the dental/medical area for removable or implantable appliances (i.e., denture base resin and facial prostheses) due to its easy fabrication, appropriate mechanical properties and relatively economical price [1 –3]. However, this material exhibits poor microbial anti-adhesive and mechanical properties, which can cause failure in dental/medical restoration [4,5]. One of the most recent and intriguing approaches used to overcome these limitations is the application of nanoadditives in the form of nanoparti cles, nanofibers, or nanotubes [6,7].
Source: Dental Materials - Category: Materials Science Authors: Source Type: research