Supplement warning: Overdosing on this to lower high blood pressure could be deadly
SUPPLEMENTS popularly used include vitamin C, vitamin D3 and omega-3 - and potassium may also be taken to ward off high blood pressure, heart disease, stroke, arthritis, cancer, digestive disorders, and infertility. However, too much of the mineral could be deadly.
Authors: Alanazy MH, Barakeh RB, Asiri A, Edrees MF, Abuzinadah AR, Aljafen BN, Muayqil T Abstract Only a small fraction of patients with acute ischemic stroke receive intravenous thrombolysis (IVT). We sought to assess barriers and practice patterns in using IVT for acute ischemic stroke among neurologists in Saudi Arabia. An electronic survey was sent to all neurologists registered with the Saudi Commission for Health Specialties. A total of 148 (77.5%) neurologists responded. The most common reported barriers for IVT administration were delayed presentation to hospitals (82.4%) and unclear time of symptom onset ...
CONCLUSION: Similar to stroke units, inpatients in a specialised brain injury unit spend large parts of the day sedentary, alone and doing non-therapeutic activities. Strategies need to be evaluated to address this problem, particularly for people with greater physical dependence. PMID: 29667440 [PubMed - as supplied by publisher]
Conclusion: This paper addresses the clinical implications of performing numerous CT examinations in patients with cancer, providing clinicians with information regarding methods to reduce risk factors in this patient population.Blood Purif 2018;46:56 –69
Conclusions: RDLs are frequently observed in high-risk patients for gastric cancer after eradication. M-NBI demonstrated significantly superior diagnostic efficacy with respect to RDL.Digestion 2018;98:48 –55
This study showed that ESE-16 exposure leads to the aggregation of acidic vesicles, identified as lysosomes, not accompanied by an induction of autophagy. Therefore, ESE-16 disrupts normal endocytic vesicle maturation likely through the inhibition of the microtubule function.Pharmacology 2018;102:9 –16
Preclinical and clinical studies have shown that viral-based immunotherapy has the potential to overcome resistance to immune checkpoint blockade (ICB) and to fill the unmet needs of many cancer patients. Poxviruses, such as modified vaccinia virus Ankara (MVA), have the potential as cancer immunotherapeutic agents. We recently showed that intratumoral (IT) delivery of inactivated modified vaccinia virus Ankara (iMVA) induces antitumor systemic immunity via the STING-mediated cytosolic DNA-sensing pathway and Batf3 –dependent CD103+/CD8+ dendritic cells (DCs).
Skin cancer is one of the most preventable forms of cancer. Roughly, 85% of skin cancer cases could be avoided by reducing UV exposure, especially during adolescence. We conducted a pilot study to evaluate sun safety behaviors in this age group, as well as, the effects of an innovative intervention in changing sun protection attitudes and behaviours. Methods: Participants were recruited from 8 secondary schools in Vancouver, BC. Participants were segregated into the control arm (N=38) or intervention arm (N=138).
Annabelle Y. Guo, PhD1, Indra Neil Sarkar, PhD1,3, Elizabeth S. Chen, PhD1,3,Joanna Walker, MD2, Paul Stey, PhD3, Wen Qing Li, PhD2, Eunyoung Cho, ScD2, Abrar A. Qureshi, MD21The Warren Alpert Medical School; 2Department of Dermatology; 3Center for Biomedical Informatics, Brown University, Providence, RI. Merkel Cell Carcinoma (MCC) is an aggressive malignant skin cancer with a high mortality rate. The effect of ultraviolet (UV) exposure on MCC patients long-term survival is not fully understood.
Background: The high keratinocyte carcinoma (KC) incidence in Western countries puts pressure on healthcare systems and urges to identify areas for improvement. Aim: To describe current KC care based on routinely collected data in primary and secondary care in the Netherlands. Methods: A retrospective cohort study using the Integrated Primary Care Information database and for specialist care the nationwide Netherlands Cancer Registry. In primary care 1736 records of patients with suspicious KC lesions were included (2009-2013).
Frequent use of sun-protection factor (SPF)>15 sunscreen is an important skin cancer prevention strategy, but little is known about users of SPF15 SPF versus