Laryngeal tuberculosis: a forgotten disease
A 93-year-old woman presented with a 2-month history of hoarseness and cough. The patient had never received immunosuppressive treatment, was serologically negative for HIV and hepatitis, and did not have a family history of tuberculosis. Laryngoscopy showed an ulcerated and granular lesion in the ventricular folds, larynx vestibule and bilateral vocal cords (Figure 1A). Histological analysis of the biopsy specimen revealed granulomas with caseating necrotic centers and Langhans giant cells without carcinoma. Ziehl-Neelsen staining of the bronchoalveolar lavage fluid revealed acid-fast bacilli and PCR using the fluid revealedMycobacterium tuberculosis. High-resolution chest computed tomography showed micronodular lesions in the right lung and a lesion suggestive of tuberculosis in the apex (Figure 1B). The patient received a standard 6-month anti-tuberculous treatment (rifampicin, isoniazid, pyrazinamide, and ethambutol). Tuberculosis is an infectious disease that is caused byM.tuberculosis. Although laryngeal tuberculosis only accounts for ∼1% of all tuberculosis cases, laryngeal tuberculosis is terrific contagious.1 Laryngeal tuberculosis has been considered to be the result of extra-pulmonary manifestations, and has often been associated with pulmonary tuberculosis. Thus, laryngeal tuberculosis should be suspected in all patients with chronic cough, hoarseness and significant dysphagia. The symptoms are often limited, although the diagnosis can be confirmed using adequ...
This review assessed and compared the efficacy and safety of DAA therapy among the elderly and younger patients with chronic HCV infection. Are results comparable?Liver International
This review provides an overview of the current evidence supporting the use of combination therapies for chronic HBV, summarizing expert consensus on a roadmap to attain functional cure.Journal of Viral Hepatitis
Conclusion: MDCT provides good results in detecting sinus fat, venous invasion and kidney-confined tumors, but evaluation of perinephric fat remains a difficult task, leading to reduced accuracy in T3a staging. PMID: 31607203 [PubMed - as supplied by publisher]
ConclusionThe tumour is notorious to cause local recurrence and metastases; hence, an early and accurate diagnosis, surgical and adjunctive chemoradiation and regular periodic follow-ups are of utmost importance for the successful management of sebaceous gland carcinoma of eyelids.
This study was aimed to estimate the length of the MIC in the interforaminal safe zone, to analyse its course in relation to the lingual and the buccal cortical plates of the mandible using cone beam computed tomography (CBCT) scans and to relate the above findings to age, gender, dental status and Malaysian races.MethodsRetrospective analysis of 100 CBCT scans (n = 200) was performed on both sides of the mandible. Cross-sectional and panoramic images were reconstructed. The length of the MIC and the horizontal distances between the MIC and the buccal and the lingual cortical plates were measured at the three...
Canada is set to expand legalization of regulated, recreational cannabis products, including edibles and vaping products. But public health experts are worried over the outbreak of vaping-related illnesses in the U.S.
Conclusion Marjolin ulcer is a high-risk skin tumor. Patients with positive lymph node or with moderately differentiated squamous cell carcinoma have high chances of recurrence. Frequent and intense follow-up is required for at least 2 years.
We present a case of MEC involving the palatal minor salivary gland of an adolescent patient successfully reconstructed using buccal myomucosal flap. The subject presented as a 17-year-old male with a painless left hard palatal mass found to have imaging suspicious for minor salivary gland tumor and punch biopsy consistent with a low-grade MEC. The subject underwent wide local excision of a 1.0 × 1.2 cm mass with 1.0 cm margins down to hard palate nasal mucosa excluding the abutting first and second molars of the ipsilateral maxilla. Pathology confirmed low-grade MEC confined to hard palate. Two weeks, thereafter, th...
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