Neurodegenerative disorders: SRC-ABL inhibitors protect motor neurons

Nature Reviews Drug Discovery 16, 530 (2017). doi:10.1038/nrd.2017.144 Author: Sarah Crunkhorn Currently approved therapies for amyotrophic lateral sclerosis (ALS) — a progressive neurodegenerative disease characterized by loss of motor neurons — exhibit limited effectiveness. By screening a panel of existing drugs in induced pluripotent stem cell (iPSC)-derived motor neurons from patients with familial ALS, Imamura et
Source: Nature Reviews Drug Discovery - Category: Drugs & Pharmacology Authors: Tags: Research Highlight Source Type: research