Fight Aging! Newsletter, July 31st 2017

In conclusion, documentation is important, a critical part of advocacy and the development process at the larger scale. It isn't just words, but rather a vital structural flow of information from one part of the larger community to another, necessary to sustain progress in any complex field. We would all do well to remember this - and to see that building this documentation is an activity in which we can all pitch in to help. Evidence Suggests that, at Least in Earlier Stages, Alzheimer's Disease Blocks Rather than Destroys Memories For years now, evidence has accumulated to suggest that Alzheimer's disease blocks memory retrieval rather than destroying memories, at least in the earlier stages prior to the onset of widespread destruction of neurons. Today's research is more of the same. This and related results raise the hope that success in any of the mainstream efforts to treat the causes of this disease should restore much of the cognitive function lost to the condition. Of course it is worth recalling that Alzheimer's patients rarely suffer Alzheimer's alone: it usually arrives alongside one or more other forms of neurodegeneration, each with distinct mechanisms that cause neurons to malfunction or be destroyed. This is in part because Alzheimer's disease is to some degree a lifestyle condition; not as grea...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs

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Publication date: Available online 13 July 2019Source: Pathology - Research and PracticeAuthor(s): Lan Luan, Hongying Wang, Beibei Zhao, Fan Wang, Juan Shi, Xiajun XuAbstractThis updated meta-analysis was performed to evaluate the relationship of a common polymorphism (T309 G, rs2279744 T > G) in the murine double minute 2 (MDM2) gene with susceptibility and prognosis of non-small cell lung cancer (NSCLC). The Cochrane Library, PubMed, Embase, CNKI, WanFang and CNKI databases were searched comprehensively for related study. Odds ratios (ORs) with their 95% confidence intervals (95% CI) were c...
Source: Pathology Research and Practice - Category: Pathology Source Type: research
Publication date: Available online 13 July 2019Source: Journal of Clinical Orthopaedics and TraumaAuthor(s): Nipith Charoenngam, Arash Shirvani, Michael F. HolickAbstractVitamin D plays an essential role in regulating calcium and phosphate metabolism and maintaining a healthy mineralized skeleton. Humans obtain vitamin D from sunlight exposure, dietary foods and supplements. There are two forms of vitamin D: vitamin D3 and vitamin D2. Vitamin D3 is synthesized endogenously in the skin and found naturally in oily fish and cod liver oil. Vitamin D2 is synthesized from ergosterol and found in yeast and mushrooms. Once vitamin...
Source: Journal of Clinical Orthopaedics and Trauma - Category: Orthopaedics Source Type: research
Publication date: Available online 13 July 2019Source: European Journal of Obstetrics &Gynecology and Reproductive BiologyAuthor(s): Roberto Tozzi, Jvan Casarin, Ahmet Baysal, Ciro Pinelli, Luka Matak, N Ghanbarzadeh, Moiad Alazzam, Riccardo Garruto-Campanile, Hooman Soleymani Majd, Yakup Kilic, Matteo MorottiAbstractObjectivesTo assess the impact of multiple bowel resections on postoperative outcomes in stage IIIC-IV ovarian cancer (OC).MethodsFrom the Oxford OC database we retrieved consecutive patients who underwent bowel resection between January 2009 and November 2017. Patients were divided into two groups: single...
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - Category: OBGYN Source Type: research
ConclusionsAIP might be a strong and independent predictor for Mets in an urban Chinese population. The incidence of Mets increased with AIP elevated in men while not in women.
Source: Nutrition, Metabolism and Cardiovascular Diseases - Category: Nutrition Source Type: research
Authors: Jose-Abrego A PMID: 31300217 [PubMed - as supplied by publisher]
Source: Annals of Hepatology - Category: Gastroenterology Tags: Ann Hepatol Source Type: research
CONCLUSION: This pilot study, conducted in India, revealed valid positive results for a promising new technology. The manual preparation of platelet-rich plasma could be automated in the future to allow a larger sample size. PMID: 31296273 [PubMed - as supplied by publisher]
Source: Journal of Laryngology and Otology - Category: ENT & OMF Tags: J Laryngol Otol Source Type: research
This study is registered with, number NCT03461757, and is closed to accrual.FindingsBetween Feb 27 and Aug 28, 2018, 1811 participants were recruited and assessed for eligibility. 1466 participants were randomly assigned to the rimegepant (n=732) or placebo (n=734) groups, of whom 1375 received treatment with rimegepant (n=682) or placebo (n=693), and 1351 were evaluated for efficacy (rimegepant n=669, placebo n=682). At 2 h postdose, rimegepant orally disintegrating tablet was superior to placebo for freedom from pain (21% vs 11%, p
Source: The Lancet - Category: General Medicine Source Type: research
ConclusionsAmong both patient groups, phentermine was more effective in achieving weight loss. Lorcaserin had dyslipidemia improvements only, among surgical patients who achieved significant weight reduction. Anti-obesity medications as part of weight management programs can result in weight loss among non-surgical and surgical patients, or halt weight regain among surgical patients.
Source: Annals of Medicine and Surgery - Category: General Medicine Source Type: research
Publication date: Available online 13 July 2019Source: Annals of Medicine and SurgeryAuthor(s): Shah Fahad, Pervaiz Hashmi, Muhammed Zohaib Nawaz Khan, Talal AqueelAbstractBackgroundThe standard treatment of displaced femoral neck fracture is arthroplasty. THA is reportedly superior to BHA in terms of hip pain, function and reoperation rate. On the other hand THA has a higher rate of dislocation. Total hip replacement with dual mobility cup increases the range of motion and reduces the chances of dislocation. The aim of this study is to compare the functional outcome, rate of dislocation, complications and mortality betwee...
Source: Annals of Medicine and Surgery - Category: General Medicine Source Type: research
Authors: Park JJ, Won S PMID: 31295992 [PubMed]
Source: Clinical and Experimental Otorhinolaryngology - Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research
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