The Marulu Strategy 2008-2012: overcoming Fetal Alcohol Spectrum Disorder (FASD) in the Fitzroy Valley.
CONCLUSIONS: Community control of public health initiatives can be achieved when Aboriginal communities prioritise issues of significant concern, and engage strategic partners to overcome them. Implications for public health: The Marulu Strategy forms a template for action to address FASD and other public health issues in Aboriginal communities in Australia and internationally. PMID: 28749590 [PubMed - as supplied by publisher]
In conclusion, data show that only specific and continuing updating for health care professionals about drinking habits may have impactful actions to prevent gestational alcohol intake in order to prevent the main cause of mental retardation in western countries. PMID: 32202545 [PubMed - in process]
CONCLUSIONS: These data confirm previous reports linking PAE to poorer spatial navigation on the VWM and are the first to provide direct evidence that volume reductions in this region partially mediate the relation of FASD diagnosis to place learning, suggesting that PAE specifically impairs the ability to encode the spatial information necessary for successful location of the hidden platform on a navigation task. PMID: 32196695 [PubMed - as supplied by publisher]
(Children's National Hospital) A research team led by Children's National Hospital faculty was able to 'rescue' a pre-clinical model of fetal alcohol spectrum disorder (FASD) in juvenile models, reversing motor skill deficits with the help of a novel drug derived from scorpion venom.
CONCLUSIONS: ARND has been a subject of debate. This analysis suggests effects of alcohol on behavior and cognition even in the absence of the characteristic facial features and growth deficiency that can be identified. Results also indicate that it may be possible to distinguish such children from those in other high risk groups. PMID: 32173870 [PubMed - as supplied by publisher]
Abstract Fetal alcohol spectrum disorders (FASD) describe a wide range of ethanol-induced developmental disabilities, including craniofacial dysmorphology, and neurochemical and behavioral impairments. Zebrafish has become a popular animal model to evaluate the long-lasting effects of, both, severe and milder forms of FASD, including alterations to neurotransmission. Glutamate is one of the most affected neurotransmitter systems in ethanol-induced developmental disabilities. Therefore, the aim of the present study was to evaluate the functionality of the glutamatergic neurotransmitter system in an adult zebrafish ...
ConclusionsThese data support choline as a potential neurodevelopmental intervention for FASD and highlight the need for long-term follow-up to capture treatment effects on neurodevelopmental trajectories.Trial registrationClinicalTrials.Gov#NCT01149538; Registered: June 23, 2010; first enrollment July 2, 2010
Fetal alcohol spectrum disorders (FASD) is an important preventable public health concern, associated to a number of common pediatric problems such as incontinence. Little is known about prevalence and presentation of incontinence in FASD, which hinders effective management.
Fetal alcohol spectrum disorders (FASD) is an important preventable public health concern, associated to a number of common pediatric problems such as incontinence. Little is known about the prevalence and presentation of incontinence in FASD, which hinders effective management.
Abstract In this issue of Alcoholism: Clinical and Experimental Research, three additional papers examining the prevalence of fetal alcohol spectrum disorders (FASD) (May et al., 2020; May et al., 2020; May et al., 2020) follow the earlier paper by Chambers et al. (2019). These studies present state-of-the-art Fetal Alcohol Spectrum Disorder (FASD) active case ascertainment of prevalence among school-age children conducted in the United States and demonstrate the importance of the behind-the-scenes intensive fieldwork necessary to complete studies of this size in community settings. PMID: 32128856 [PubMed - a...
ConclusionsThe microdeletion emphasizes the importance of adequate chromosomal testing in examining the etiology of complex alcohol ‐induced developmental disorders. Furthermore, the genotype‐specific decreased DNA methylation at theIGF2/H19 locus cannot be considered as a biological mark for PAE in adult WBCs.