Bisphosphonate-associated spontaneous osteonecrosis of maxilla: a case report

Bisphosphonate therapy can lead to late complications, such as osteonecrosis because of reduced activity of osteoclasts and changing in bone remodeling. Herein we present a case of a male patient, 47 years old, who was diagnosed with multiple myeloma and treated with zoledronic acid (4 mg intravenously monthly over 3 years). The patient presented to dental care with complaints of pain in the maxilla. On physical examination, exposed bone in the palatal region of the tooth 27 was observed. Biopsy was performed and devitalized bone confirmed.

Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - July 28, 2017 Category: ENT & OMF Authors: LAURA IZABEL LAMPERT BONZANINI, RI ÉLI ELIS SCHULZ, ELOISA BARBIERI SOLDERA, GABRIELA BARBIERI ORTIGARA, MÔNICA PAGLIARINI BULIGON, KÍVIA LINHARES FERRAZZO, JENIFER COLOMBELLI MIELKE Tags: CPP - Clinical Poster Presentation Source Type: research