Disease sleuths unmask deadly encephalitis culprit

Source: ScienceNOW - Category: Science Authors: Tags: Asia/Pacific News, Epidemiology, Medicine, Diseases, Virology In Depth Source Type: news

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This report highlights that toxoplasma can present as LESCL and needs to be considered in the differential diagnosis of atypical myelitis.
Source: Annals of Indian Academy of Neurology - Category: Neurology Authors: Source Type: research
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Source: Expert Opinion on Biological Therapy - Category: Drugs & Pharmacology Authors: Source Type: research
amada Influenza and the common cold are acute infectious diseases of the respiratory tract. Influenza is a severe disease that is highly infectious and can progress to life-threating diseases such as pneumonia or encephalitis when aggravated. Due to the fact that influenza infections and common colds spread easily via droplets and contact, public prevention measures, such as hand washing and facial masks, are recommended for influenza prophylaxis. Experimental studies have reported that tea catechins inhibited influenza viral adsorption and suppressed replication and neuraminidase activity. They were also effective aga...
Source: Molecules - Category: Chemistry Authors: Tags: Review Source Type: research
Graft versus host disease (GvHD) remains a major cause of morbidity and mortality after hematopoietic stem cell transplantation (HSCT).[1] The incidence of GvHD varies between 30% –70% in terms of donor recipient human leukocyte antigen (HLA) compatibility.[2–5] Donor T cells in the transplanted graft contribute to the development of GvHD[1,3]; thus, T cell-depleted grafts (TCD) constitute a strategy to overcome GvHD in HSCT.[6] Mobilized peripheral blood from a haploiden tical relative constitutes an alternative source when a matched HLA donor is not available.
Source: Biology of Blood and Marrow Transplantation - Category: Hematology Authors: Source Type: research
AbstractNeurotropic herpesviruses can establish lifelong infection in humans and contribute to severe diseases including encephalitis and neurodegeneration. However, the mechanisms through which the brain ’s immune system recognizes and controls viral infections propagating across synaptically linked neuronal circuits have remained unclear. Using a well-established model of alphaherpesvirus infection that reaches the brain exclusively via retrograde transsynaptic spread from the periphery, and in v ivo two-photon imaging combined with high resolution microscopy, we show that microglia are recruited to and isolate inf...
Source: Acta Neuropathologica - Category: Neurology Source Type: research
We present the case of a child with long-standing, super refractory status epilepticus (SRSE) who manifested prompt and complete resolution of SRSE upon exposure to pure cannabidiol. SRSE emerged in the context of remote suspected encephalitis with previously well-controlled epilepsy. We discuss the extent to which response may be specifically attributed to cannabidiol, with consideration and discussion of multiple potential drug–drug interactions. Based on this case, we propose that adjunctive cannabidiol be considered in the treatment of SRSE.
Source: Epilepsy and Behavior Case Reports - Category: Neurology Source Type: research
Abstract Mosquito borne diseases such as malaria, filariasis, chikunguniya, yellow fever, dengue and Japanese encephalitis are the major cause of remarkable morbidity and mortality in livestock and humans worldwide. Since ancient times, aromatic plants are used for their medicinal value. Essential oils derived from these plants may be used as effective alternatives/adjuvents in pharmaceuticals, biomedical, cosmetic, food, veterinary and agriculture applications. These oils have also gained popularity and interest for prevention and treatment of various disorders. However, several reports on adverse effects includi...
Source: Current Drug Discovery Technologies - Category: Drugs & Pharmacology Authors: Tags: Curr Drug Discov Technol Source Type: research
Vector-Borne and Zoonotic Diseases, Ahead of Print.
Source: Vector-Borne and Zoonotic Diseases - Category: Infectious Diseases Authors: Source Type: research
Vector-Borne and Zoonotic Diseases, Ahead of Print.
Source: Vector-Borne and Zoonotic Diseases - Category: Infectious Diseases Authors: Source Type: research
Liubov L. Chernokhaeva, Yulia V. Rogova, Liubov I. Kozlovskaya, Lidiya I. Romanova, Dmitry I. Osolodkin, Mikhail F. Vorovitch, Galina G. Karganova
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
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