Craniopharyngioma in a patient with acromegaly due to a pituitary macroadenoma
We present the first reported case of a craniopharyngioma as a second primary tumor in a patient with acromegaly due to a growth hormone (GH)-secreting pituitary adenoma. The patient was lost for follow-up for 18 years after trans-sphenoidal pituitary surgery for a GH-secreting pituitary adenoma. She presented with headaches and decreased visual acuity, and showed unsuppressed GH in an oral glucose load test with high IGF-1 levels. Brain MRI showed a suprasellar cystic mass and the patient underwent surgery for cyst drainage resulting in postoperative improvement in her vision. Biopsy of the mass confirmed the diagnosis of a craniopharyngioma. We stress the need for close follow-up of patients with acromegaly with adequate control of GH and IGF-1 levels.
New findings cast doubt on the use of hydromorphone as first-line therapy for acute migraine in the ED setting.Medscape Medical News
Abstract Recent studies suggested a link between diversity of beta tubulin isotypes in microtubule structures and the regulatory roles that they play not only on microtubules' intrinsic dynamic, but also on the translocation characteristics of some of the molecular motors along microtubules. Remarkably, unlike porcine brain microtubules, MCF7 microtubules are structured from a different beta tubulin distribution. These types of cancer microtubules show a relatively stable and slow dynamic. In addition, the translocation parameters of some molecular motors are distinctly different along MCF7 as compared to those pa...
The death of Gord Downie hits close to home for Winnipegger Jared Spier, whose partner Joanne Schiewe died from the same brain cancer that took the Tragically Hip frontman.
The death of Gord Downie hits close to home for Winnipegger Jared Spier, whose partner, Joanne Schiewe, died from the same brain cancer that took the Tragically Hip frontman.
Migraine headaches have been associated with anxiety and depression, but researchers in Taiwan have found a link between migraine frequency and mood disorders.
Scientists from Northwestern University are taking a radical approach by testing the potential for arsenic to treat a deadly form of brain cancer.
The more migraine headaches someone gets, the more intense their anxiety and depression are likely to be, according to the findings of a new Taiwanese study of 588 migraine sufferers.
Conclusions: We describe the clinical characteristics and outcomes of children with incidental MRI findings highly suggestive of CNS demyelination. Children with RIS had a substantial risk of subsequent clinical symptoms and/or radiologic evolution. The presence of oligoclonal bands in CSF and spinal cord lesions on MRI were associated with an increased risk of a first clinical event. News in Context Next: Harnessing brain scans to personalize autism-related behavioral interventions Can brain scans identify ADHD and help predict treatment response? Brain waves help predict stress-related sleep problems Cognitive therapy ...
TOXIC arsenic could be used as cheap treatment for a rare brain cancer, in a bid to triple life expectancy after diagnosis.
Immunotherapy for leukemia patients has been nothing short of a miracle. Now scientists hope to use that science and other forms of gene therapy to tackle three of the deadliest forms of cancer: glioblastoma (brain cancer), sarcoma (bone cancer) and ovarian cancer. Three scientists have received $1.3 million in critical funding from the Alliance for Cancer Gene Therapy (ACGT), the nation's only nonprofit dedicated exclusively to cell and gene therapies for cancer.