Serum Vaccine Antibody Concentrations in Adolescents Exposed to Perfluorinated Compounds

Conclusions: These results are in accord with previous findings of PFAS immunotoxicity at current exposure levels. https://doi.org/10.1289/EHP275 Received: 09 February 2016 Revised: 06 June 2016 Accepted: 12 July 2016 Published: 26 July 2017 Address correspondence to P. Grandjean, HSPH-EOME, 401 Park Dr., 3E L3-045, Boston, MA 02215 USA. Telephone: 617-384-8907. Email: pgrandjean@health.sdu.dk The authors declare they have no actual or potential competing financial interests. Note to readers with disabilities: EHP strives to ensure that all journal content is accessible to all readers. However, some figures and Supplemental Material published in EHP articles may not conform to 508 standards due to the complexity of the information being presented. If you need assistance accessing journal content, please contact ehponline@niehs.nih.gov. Our staff will work with you to assess and meet your accessibility needs within 3 working days. Introduction Perfluorinated alkylate substances (PFASs) have a wide range of applications in water-, soil-, and stain-resistant coatings for clothing and other textiles and in oil-resistant coatings for food wrapping materials, and their use for>60 y has resulted in worldwide exposure to these persistent compounds (Lindstrom et al. 2011). Epidemiological research on possible adverse effects in exposed populations has intensified only in recent years (Grandjean and Clapp 2015; Steenland et al. 2014). As a measur...
Source: EHP Research - Category: Environmental Health Authors: Tags: Research Source Type: research

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ConclusionsThe 20-year follow-up analysis of pediatric renal care services in European countries revealed that pediatric nephrology has become a well-established subspecialty in pediatrics and nephrology in 2017. The ESPN will continue its efforts to further improve pediatric renal care for European children by harmonizing remaining disparities of renal care services.
Source: Pediatric Nephrology - Category: Urology & Nephrology Source Type: research
This article analyzes the perceptions of community leaders and/or residents of a poor neighborhood in Salvador, Bahia, Brazil, regarding the State ’ s action in FNS. The methodology combined conceptual maps and focus group that were implemented in two different moments (2014 and 2016, respectively) of a participatory action research. Results highlight, at both times, the distance of local actors regarding FNS policies. At the beginning of the action research, perceptions on FNS emphasized individuals ’ responsibility, showing the unawareness on the human right to food. Two years later, narratives of the focus g...
Source: Saude e Sociedade - Category: International Medicine & Public Health Source Type: research
Resumo Este artigo avalia a rela ção de custos entre a saúde pública e a implementação do saneamento básico na capital da Guiné-Bissau. Analisaram-se seis cenários, incluindo três opções para o sistema de esgotamento sanitário (sistema coletivo com rede coletora e estação elevatória de esgoto, sistema simplificado i ndividual por latrina e sistema coletivo completo com rede coletora, estação elevatória e estação de tratamento de esgoto) e duas para o sistema de abastecimento de &...
Source: Saude e Sociedade - Category: International Medicine & Public Health Source Type: research
Resumo Este artigo avalia a rela ção de custos entre a saúde pública e a implementação do saneamento básico na capital da Guiné-Bissau. Analisaram-se seis cenários, incluindo três opções para o sistema de esgotamento sanitário (sistema coletivo com rede coletora e estação elevatória de esgoto, sistema simplificado i ndividual por latrina e sistema coletivo completo com rede coletora, estação elevatória e estação de tratamento de esgoto) e duas para o sistema de abastecimento de &...
Source: Saude e Sociedade - Category: International Medicine & Public Health Source Type: research
Resumo A Resolu ção nº 510/2016 do Conselho Nacional de Saúde determina diretrizes éticas específicas para as ciências humanas e sociais (CHS) e é resultado de anos de trabalho de pessoas e instituições que há muito apontavam a inadequação de uma única orientação de cunho biomédico para pesquisas e m diferentes áreas. Discutem-se aqui as principais diferenças entre a pesquisa em CHS e a pesquisa biomédica. A disputa pelo poder de definir o que é ciência caracteriza o campo ci...
Source: Saude e Sociedade - Category: International Medicine & Public Health Source Type: research
Resumo A Resolu ção nº 510/2016 do Conselho Nacional de Saúde determina diretrizes éticas específicas para as ciências humanas e sociais (CHS) e é resultado de anos de trabalho de pessoas e instituições que há muito apontavam a inadequação de uma única orientação de cunho biomédico para pesquisas e m diferentes áreas. Discutem-se aqui as principais diferenças entre a pesquisa em CHS e a pesquisa biomédica. A disputa pelo poder de definir o que é ciência caracteriza o campo ci...
Source: Saude e Sociedade - Category: International Medicine & Public Health Source Type: research
CONCLUSIONS The double-membrane antigen DNA vaccine SjTsp2-29 elicited protection against Schistosoma infection and might serve as a vaccine candidate. PMID: 31811711 [PubMed - in process]
Source: Medical Science Monitor - Category: Research Tags: Med Sci Monit Source Type: research
Publication date: Available online 9 December 2019Source: Social Science &MedicineAuthor(s): Maddalena Canna, Rebecca SeligmanAbstractFunctional Neurological Disorder (FND), otherwise known as Conversion Disorder, is characterized by abnormal sensory or motor symptoms that are determined to be “incompatible” with neurological disease. FND patients are a challenge for contemporary medicine. They experience high levels of distress, disability, and social isolation, yet a large proportion of those treated do not get better. Patients with FNDs are often misdiagnosed and suffer from stigma, dysfunctional medical...
Source: Social Science and Medicine - Category: Psychiatry & Psychology Source Type: research
ConclusionsThe findings highlight the acceptability of physical activity as a mental health intervention tool within a post-secondary context. Importantly the results provide implications for developing strategies to incorporate physical activity as an acceptable support method within mental health services.
Source: Mental Health and Physical Activity - Category: Psychiatry & Psychology Source Type: research
This study aimed to determine what proportion of children’s dietary intake occurs within the ECE setting and whether diet quality is higher at ECE centers and, consequently, on weekdays than weekends.DesignThis cross-sectional analysis of a larger cluster randomized controlled trial used multiple 24-hour dietary intakes measured through a combination of the Dietary Observation in Child Care protocol and parent-reported food diaries.Participants/settingParticipants (N=840) included children aged 3 to 4 years enrolled in ECE centers in central North Carolina for whom 24-hour dietary intake was captured via observation ...
Source: Journal of the Academy of Nutrition and Dietetics - Category: Nutrition Source Type: research
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