Transcranial ultrasonic stimulation modulates single-neuron discharge in macaques performing an antisaccade task

Low intensity transcranial ultrasonic stimulation (TUS) has been demonstrated to non-invasively and transiently stimulate the nervous system. Although US neuromodulation has appeared robust in rodent studies, the effects of US in large mammals and humans have been modest at best. In addition, there is a lack of direct recordings from the stimulated neurons in response to US. Our study investigates the magnitude of the US effects on neuronal discharge in awake behaving monkeys and thus fills the void on both fronts.

Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - July 26, 2017 Category: Neurology Authors: Nicolas Wattiez, Charlotte Constans, Thomas Deffieux, Pierre M. Daye, Mickael Tanter, Jean-Fran çois Aubry, Pierre Pouget Source Type: research