Evidence for large-scale gene-by-smoking interaction effects on pulmonary function

Conclusions: This study highlights the benefit of using genetic risk scores for identifying interactions missed when studying individual SNPs and shows, for the first time, that persons with the highest genetic risk for low FEV1/FVC may be more susceptible to the deleterious effects of smoking.
Source: International Journal of Epidemiology - Category: Epidemiology Source Type: research