Obesity and its implications on oncological urological surgery

Purpose of review: To review and summarize the contemporary knowledge of the implications of obesity on perioperative outcomes in oncological urologic surgeries. Recent findings: In men undergoing radical prostatectomy, obesity seems to confer a higher risk of intraoperative bleeding, biochemical recurrence, urinary incontinence, and postoperative erectile dysfunction. The literature was not consistent regarding the benefits of a minimally invasive approach in overweight and obese patients. Similarly, available data suggest a higher risk of complications in obese patients undergoing radical cystectomy. Obesity does not seem to confer a higher risk of morbidity in patients undergoing radical nephrectomy and nephroureterectomy. However, studies reported conflicting surgical outcomes in obese patients treated with partial nephrectomy. Overweight and obesity status are associated with higher morbidity in patients treated with inguinal lymph node dissection for penile cancer. No data are available regarding the impact of obesity in obese patients treated with retroperitoneal lymph node dissection for testicular cancer. Summary: Although randomized clinical data are lacking and the results of many studies are inconsistent, evidence supports the feasibility and safety of different oncological urological surgeries in obese patients. Nevertheless, obesity is an important comorbidity associated with a higher morbidity rate in most oncological urological surgeries.
Source: Current Opinion in Urology - Category: Urology & Nephrology Tags: OBESITY AND ITS IMPACT ON UROLOGICAL DISEASE: Edited by Richard K. Lee and Christian Seitz Source Type: research

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Source: Photochemistry and Photobiology - Category: Science Authors: Tags: SPECIAL ISSUE RESEARCH ARTICLE Source Type: research
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Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Other Homo sapiens Source Type: research
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Source: Journal of Functional Foods - Category: Nutrition Source Type: research
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Source: Journal of Coloproctology - Category: Gastroenterology Source Type: research
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Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
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Source: Biorheology - Category: Biochemistry Tags: Biorheology Source Type: research
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Source: Drug Metabolism Reviews - Category: Drugs & Pharmacology Tags: Drug Metab Rev Source Type: research
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Source: Materials Today: Proceedings - Category: Materials Science Source Type: research
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Source: Obesity Research and Clinical Practice - Category: Eating Disorders & Weight Management Source Type: research
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Source: Journal of Dietary Supplements - Category: Nutrition Tags: J Diet Suppl Source Type: research
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