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Sequential Therapy of Breast Cancer Cell Lines with Vitamin C and Quercetin Improves the Efficacy of Chemotherapeutic Drugs

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Source: Nutrition and Cancer - Category: Cancer & Oncology Authors: Source Type: research

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Authors: Li WX, Sha RL, Bao JQ, Luan W, Su RL, Sun SR Abstract OBJECTIVE: Long noncoding RNA linc-ITGB1 (linc-ITGB1) was reported to serve as a tumor promoter in breast cancer (BC). However, the clinical significance of linc-ITGB1 has not been reported. The present study aimed to determine the relationship between linc-ITGB1 expression and clinicopathological features and survival. PATIENTS AND METHODS: qRT-PCR was used to quantify the expression levels of linc-ITGB1 in BC and adjacent non-cancerous breast tissues. The X2 test was performed to determine the associations between linc-ITGB expression and the clin...
Source: European Review for Medical and Pharmacological Sciences - Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
CONCLUSION: According to our results, malignancy and chemotherapy will have an important effect on the immune system and cause negative response to HBV vaccination. Our results revealed the importance of passive immunity and screening for HBV infection in patients undergoing chemotherapy. Also more studies for better vaccination schedules in this group of patients are recommended. PMID: 28828339 [PubMed]
Source: Biomed Res - Category: Research Authors: Tags: Adv Biomed Res Source Type: research
AbstractMolecular subtyping in breast cancer is recently emerging as an important determinant of treatment and outcomes, and triple negative breast cancer (TNBC) has been established as a distinct clinical entity with unique features and adverse outcomes. A retrospective analysis of a prospectively maintained computerized breast cancer database was performed, and all the non-metastatic female breast cancer patients undergoing potentially curative multimodality treatment between 2005 and 2012 were included for analysis. Patients with incomplete information regarding ER, PR, and HER2/neu status were excluded. All the eligibl...
Source: Indian Journal of Surgical Oncology - Category: Cancer & Oncology Source Type: research
This article is protected by copyright. All rights reserved
Source: Journal of Cellular Physiology - Category: Cytology Authors: Tags: ORIGINAL RESEARCH ARTICLE Source Type: research
Authors: Pindiprolu SKSS, Krishnamurthy PT, Chintamaneni PK, Karri VVSR Abstract Breast cancer stem cells (BCSCs) are heterogeneous subpopulation of tumour initiating cells within breast tumours. They are spared even after chemotherapy and responsible for tumour relapse. Targeting BCSCs is, therefore, necessary to achieve radical cure in breast cancer. Despite the availability of agents targeting BCSCs, their clinical application is limited due to their off-target effects and bioavailability issues. Nanotechnology based drug carriers (nanocarriers) offer various advantages to deliver anti-BCSCs agents specifically ...
Source: Artificial Cells, Nanomedicine and Biotechnology - Category: Biotechnology Tags: Artif Cells Nanomed Biotechnol Source Type: research
Cancer patients who opt for alternative therapy instead of conventional medicine significantly decrease their chances of survival, according to researchers at Yale School of Medicine. Although the popularity of alternative medicine continues to grow, a recent study published in the Journal of the National Cancer Institute found survival rates significantly reduced for those who use it as first-line therapy. Conventional cancer treatments — chemotherapy, surgery and radiation — still produce a much better chance of survival. Mesothelioma was not included in the study, but the findings are relevant to this rare ...
Source: Asbestos and Mesothelioma News - Category: Environmental Health Authors: Tags: acupuncture cancer Alternative medicine alternative mesothelioma treatment alternative therapy survival alternative vs conventional medicine breast cancer colon cancer Conventional cancer treatments Dr. David Gorski Dr. Skyler Johnson Source Type: news
It has come to our attention that some submissions to the competition may not have reached us. We are investigating this issue, but if you have previously submitted your photographs, we encourage you to resubmit to researchinprogress@biomedcentral.com. In light of this, we are extending our competition deadline to the 17th September. About the competition We are looking for inspiring photographs that reflect innovation, curiosity and integrity in the following categories relating to research: People at work Close-ups of equipment Plants and animals Microscopy Anyone interested in research and photography can enter from a...
Source: BioMed Central Blog - Category: General Medicine Authors: Tags: Open Access Publishing Source Type: blogs
[SAnews.gov.za] Health Minister Dr Aaron Motsoaledi will on Friday launch cervical and breast cancer policies aimed at addressing the high mortality caused by these two types of cancers.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
[SNA] Khartoum -The Federal Health Minister, Bahar Idriss abu-Garda, has revealed the start of importation of a new drug for the treatment of breast and lymph nodes and storing it in the medical supplies stores at the cost of 80 million pounds.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
PMID: 28825398 [PubMed - in process]
Source: Reviews on Recent Clinical Trials - Category: Cancer & Oncology Authors: Tags: Rev Recent Clin Trials Source Type: research
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