Lifetime PTSD and Geriatric Depression Symptomatology Relate to Altered Dorsomedial Frontal and Amygdala Morphometry

Posttraumatic stress disorder (PTSD) affects a large portion of combat deployed Veterans. Moreover, many individuals also suffer from comorbid late life depression (geriatric depression; GD). While a great deal of research has begun to characterize the morphometric features of PTSD and depression individually, few studies have investigated the interacting effect of these two disorders, specifically in a Veteran population. The current study used cortical and subcortical surface-based morphometry (SBM) in combination with psychological assessments of PTSD and GD symptom severity to examine morphometric alterations in Vietnam War Veterans.

Source: Psychiatry Research: Neuroimaging - July 25, 2017 Category: Psychiatry Authors: Lindsay K. Knight, Farah Naaz, Teodora Stoica, Brendan E. Depue, for the Alzheimer ’s Disease Neuroimaging Initiative Source Type: research