Nuclear maspin expression: a biomarker for budding assessment in colorectal cancer specimens

Conclusion For the colorectal carcinomas, the infiltrative aspect at macroscopic evaluation and nuclear maspin in the buds might be used as indicators of risk for lymph node metastases. Maspin nuclear expression in the buds may be helpful for a proper budding assessment and may serve as a negative prognostic factor.
Source: Pathology Research and Practice - Category: Pathology Source Type: research