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Senior Health Information

As many of you know, the NIH Senior Health website will be discontinued as of August 1. As unfortunate as it is to lose this great resource, other senior health information resources do exist. Not all of these are National Library of Medicine (NLM) resources but do provide an array of information pertaining to aging and health for seniors themselves, for caregivers and for those whose work focuses on older adult concerns. MedlinePlus provides information with a Seniors demographic group which includes a listing of health topics related to this age group. The NIH National Institute on Aging provides a number of resources for Seniors. The Health &Aging tab includes links to: A-Z health topics listing Aging &Health news stories Clinical Trial information ADEAR (Alzheimer’s Disease and Education Referral Center) provides a variety of information for caregivers and providers Go4Life- an exercise, nutrition, and safety resource to help motivate seniors to stay healthy Health information in Spanish and other languages American Indian Health provides culturally appropriate health information for elders. NIHSeniorHealth YouTube Channel will continue to offer its 110+ videos about a variety of health and wellness information. NLM4Caregivers provides links to health and other relevant information needed by caregivers to assist for a variety of needs. National Resource Center on LGBT Aging provides training, technical assistance, and educational resources&n...
Source: Dragonfly - Category: Databases & Libraries Authors: Tags: Health Literacy/Consumer Health News from NLM News From NN/LM PNR Public Libraries Source Type: news

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In this study, we observed an altered neuroinflammatory milieu in the hippocampus of the TS mouse model. Pro-inflammatory mediators that were elevated in the hippocampus of this model included pro-inflammatory cytokine IL17A, which has a fundamental role in mediating brain damage in neuroinflammatory processes. Here, we analyzed the ability of an anti-IL17A antibody to reduce the neuropathological alterations that are present in TS mice during early neurodevelopmental stages (i.e., hippocampal neurogenesis and hypocellularity) or that are aggravated in later-life stages (i.e., cognitive abilities, cholinergic neuronal loss...
Source: Brain, Behavior, and Immunity - Category: Neurology Authors: Tags: Brain Behav Immun Source Type: research
The objective here is a set of tests that (a) match up to the expected outcome based on human trials of mitochondrially targeted antioxidants, and (b) that anyone can run without the need to involve a physician, as that always adds significant time and expense. These tests are focused on the cardiovascular system, particularly measures influenced by vascular stiffness, and some consideration given to parameters relevant to oxidative stress and the development of atherosclerosis. A standard blood test, with inflammatory markers. An oxidized LDL cholesterol assessment. Resting heart rate and blood pressure. Heart r...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Alzheimer ’s disease destroys brain cells in part by promoting the formation of insoluble clumps that contain a protein called tau. Not only are these “tau aggregates” toxic for the cells that harbor them, but they also invade and destroy neighboring brain cells, or neurons, which speeds the cognitive d ecline associated with the Alzheimer’s.For those reasons, Alzheimer ’s researchers have been intensely interested in therapies aimed at either preventing tau aggregation or blocking its spread.Now, researchers at theUCLA School of Nursing and the department of neurology at theDavid Geffen Schoo...
Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news
Many of the methods by which aging can be modestly slowed in laboratory species are characterized by increased cellular housekeeping: more repair, more clearance of broken molecular machinery, more removal of metabolic waste. The extended life span produced by calorie restriction appears to depend on this increase: it doesn't happen in mice in which housekeeping processes are disabled. Most of the work on cellular housekeeping in aging is focused on autophagy, responsible for removing protein aggregates and cellular structures. The proteasome is a part of a separate system of housekeeping that deals with broken or otherwis...
Source: Fight Aging! - Category: Research Authors: Tags: Medicine, Biotech, Research Source Type: blogs
Abstract Neurodegenerative diseases are hereditary or sporadic conditions that result in the progressive loss of the structure and function of neurons as well as neuronal death. Although a range of diseases lie under this umbrella term, Alzheimer's disease (AD) and Parkinson's disease (PD) are the most common neurodegenerative diseases that affect a large population around the globe. Alzheimer's disease is characterized by the abnormal accumulation of extracellular amyloid-β plaques and intraneuronal neurofibrillary tangles in brain regions and manifests as a type of dementia in aged individuals that results ...
Source: Biomed Res - Category: Research Authors: Tags: Biomed Res Int Source Type: research
Abstract Traumatic brain injury (TBI) remains a major cause of death and disability worldwide. Increasing evidence indicates that TBI is an important risk factor for neurodegenerative diseases including Alzheimer's disease, Parkinson's disease, and chronic traumatic encephalopathy. Despite improved supportive and rehabilitative care of TBI patients, unfortunately, all late phase clinical trials in TBI have yet to yield a safe and effective neuroprotective treatment. The disappointing clinical trials may be attributed to variability in treatment approaches and heterogeneity of the population of TBI patients as well...
Source: Chinese Journal of Traumatology - Category: Orthopaedics Authors: Tags: Chin J Traumatol Source Type: research
In conclusion, a debate exists on whether aging is a disease in itself. Some authors suggest that physiological aging (or senescence) is not really distinguishable from pathology, while others argue that aging is different from age-related diseases and other pathologies. It is interesting to stress that the answer to this question has important theoretical and practical consequences, taking into account that various strategies capable of setting back the aging clock are emerging. The most relevant consequence is that, if we agree that aging is equal to disease, all human beings have to be considered as patients to be treat...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
A study of nearly 2.8 million adults spanning 36 years suggests that people with traumatic brain injury (TBI) are more likely to develop dementia than those with no history of TBI. Thefindings, which were published this week inLancet Psychiatry, demonstrate the heightened risk of dementia years following a TBI.TBI affects 47 million people globally and is a major cause of mortality and disability, yet large-scale studies with long follow-up have been sparse, wrote lead author Jesse Fann, M.D., M.P.H., a professor of psychiatry and behavioral sciences at the University of Washington School of Medicine, and colleagues. The r...
Source: Psychiatr News - Category: Psychiatry Tags: Danish Civil Registration System dementia fracture Jesse Fann Lancet Psychiatry TBI traumatic brain injury Source Type: research
This case-control study investigates the prevalence and type of learning disability in a cohort of patients with posterior cortical atrophy compared with patients with logopenic variant primary progressive aphasia and amnestic Alzheimer disease.
Source: JAMA Neurology - Category: Neurology Source Type: research
Alzheimer's disease (AD) is the most common form of dementia and a leading cause of disability in late life (Prince  et al., 2013). Despite cognitive symptoms being the hallmark of the disease, depression is common affecting around half of patients at some point during the illness (Di Iulio et al., 2010). Systematic review data (Chi et al., 2015) indicate that estimates of prevalence of major depression in Alzheimer's disease vary by diagnostic approaches, with estimates of 12.7% using DSM-IV criteria (American Psychiatric Association, 1994), versus rates of over 40% in studies emplo...
Source: Journal of Affective Disorders - Category: Neurology Authors: Source Type: research
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