Senior Health Information

As many of you know, the NIH Senior Health website will be discontinued as of August 1. As unfortunate as it is to lose this great resource, other senior health information resources do exist. Not all of these are National Library of Medicine (NLM) resources but do provide an array of information pertaining to aging and health for seniors themselves, for caregivers and for those whose work focuses on older adult concerns. MedlinePlus provides information with a Seniors demographic group which includes a listing of health topics related to this age group. The NIH National Institute on Aging provides a number of resources for Seniors. The Health &Aging tab includes links to: A-Z health topics listing Aging &Health news stories Clinical Trial information ADEAR (Alzheimer’s Disease and Education Referral Center) provides a variety of information for caregivers and providers Go4Life- an exercise, nutrition, and safety resource to help motivate seniors to stay healthy Health information in Spanish and other languages American Indian Health provides culturally appropriate health information for elders. NIHSeniorHealth YouTube Channel will continue to offer its 110+ videos about a variety of health and wellness information. NLM4Caregivers provides links to health and other relevant information needed by caregivers to assist for a variety of needs. National Resource Center on LGBT Aging provides training, technical assistance, and educational resources&n...
Source: Dragonfly - Category: Databases & Libraries Authors: Tags: Health Literacy/Consumer Health News from NLM News From NN/LM PNR Public Libraries Source Type: news

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In conclusion, this is the first report to show that pyroptotic cell death occurs in the aging brain and that the inflammasome can be a viable target to decrease the oxidative stress that occurs as a result of aging. Reducing Levels of Protein Manufacture Slows Measures of Aging in Nematodes https://www.fightaging.org/archives/2018/12/reducing-levels-of-protein-manufacture-slows-measures-of-aging-in-nematodes/ Researchers here demonstrate that an antibiotic slows aging in nematode worms, providing evidence for it to work through a reduction in protein synthesis. Beyond a slowing of aging, one of the con...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Authors: Ortiz A, Sanchez-Niño MD, Crespo-Barrio M, De-Sequera-Ortiz P, Fernández-Giráldez E, García-Maset R, Macía-Heras M, Pérez-Fontán M, Rodríguez-Portillo M, Salgueira-Lazo M, Sánchez-Álvarez E, Santamaría-Olmo R, Simal-Blanco F, Pino-Pino MD Abstract The Global Burden of Disease (GBD) study measures the health of populations worldwide and by country on an annual basis and aims at helping guide public policy on health issues. The GBD estimates for Spain in 2016 and recent trends in mortality and morbidity from 2006 to 2016 were recent...
Source: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia - Category: Urology & Nephrology Tags: Nefrologia Source Type: research
AbstractNicotinamide adenine dinucleotide (NAD) supplementation to repair the disabled mitochondria is a promising strategy for the treatment of Alzheimer ’s disease (AD) and other dementia. Nicotinamide ribose (NR) is a safe NAD precursor with high oral bioavailability, and has beneficial effects on aging. Here, we applied NR supplied food (2.5 g/kg food) to APP/PS1 transgenic AD model mice and aged mice for 3 months. Cognitive function, locomoto r activity and anxiety level were assessed by standard behavioral tests. The change of body weight, the activation of microglia and astrocytes, the accumulation o...
Source: Metabolic Brain Disease - Category: Neurology Source Type: research
DiscussionDietary changes initiated during the intervention were related to changes in executive function in 2 years. Long-term diet appeared more influential for global cognition.
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - Category: Geriatrics Source Type: research
This article, however, is more of a commentary on high level strategy and the effects of regulation, coupled with a desire to forge ahead rather than hold back in the matter of treating aging, thus I concur with much more of what is said than is usually the case. For decades, one of the most debated questions in gerontology was whether aging is a disease or the norm. At present, excellent reasoning suggests aging should be defined as a disease - indeed, aging has been referred to as "normal disease." Aging is the sum of all age-related diseases and this sum is the best biomarker of aging. Aging and its d...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Publication date: Available online 26 November 2018Source: The Lancet NeurologyAuthor(s): Emma Nichols, Cassandra E I Szoeke, Stein Emil Vollset, Nooshin Abbasi, Foad Abd-Allah, Jemal Abdela, Miloud Taki Eddine Aichour, Rufus O Akinyemi, Fares Alahdab, Solomon W Asgedom, Ashish Awasthi, Suzanne L Barker-Collo, Bernhard T Baune, Yannick Béjot, Abate B Belachew, Derrick A. Bennett, Belete Biadgo, Ali Bijani, Muhammad Shahdaat Bin Sayeed, Carol BrayneSummaryBackgroundThe number of individuals living with dementia is increasing, negatively affecting families, communities, and health-care systems around the world. A succ...
Source: The Lancet Neurology - Category: Neurology Source Type: research
ConclusionsThe incidence of vitamin B12 use was considerably higher among persons with AD than in persons without AD around the time of AD diagnosis. On the other hand, the incidence of vitamin B12 use increased during the follow-up also in persons without AD. Regular checks of vitamin B12 levels among older people and earlier treatment of deficiency might reduce the disability related to vitamin B12 deficiency.
Source: Journal of Public Health - Category: Health Management Source Type: research
This study is the culmination of a decade of research that has repeatedly demonstrated that this vaccine can effectively and safely target in animal models what we think may cause Alzheimer's disease. I believe we're getting close to testing this therapy in people." Although earlier research established that antibodies significantly reduce amyloid buildup in the brain, researchers needed to find a safe way to introduce them into the body. A vaccine developed elsewhere showed promise in the early 2000s, but when tested in humans, it caused brain swelling in some patients. The new idea was to start with DNA codin...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
In this study, angiopoietin-1, an endothelial growth factor crucial for vascular development and angiogenesis, and the integrin αvβ3 binding peptide C16, which inhibits inflammatory cell infiltration, were utilized to improve the local microenvironment within the central nervous system of an ALS/PDC rodent model by minimizing inflammation. Our results revealed that L-serine application yielded better effects than C16+ angiopoietin-1 treatment alone for alleviating apoptotic and autophagic changes and improving cognition and electrophysiological dysfunction, but not for improving the inflammatory micro-environmen...
Source: Aging - Category: Biomedical Science Authors: Tags: Aging (Albany NY) Source Type: research
Publication date: Available online 22 November 2018Source: Pharmacological ResearchAuthor(s): Kai Zhang, Jia LuoAbstractAlcohol abuse causes profound damage to both the developing brain and the adult brain. Prenatal exposure to alcohol results in a wide range of deficits known as fetal alcohol spectrum disorders (FASD). Alcohol abuse in adults is associated with brain shrinkage, memory and attention deficits, communication disorders and physical disabilities. Monocyte chemoattractant protein-1 (MCP-1/CCL2) is one of the key chemokines that regulate the recruitment and activation of monocytes and microglia. Both MCP-1 and i...
Source: Pharmacological Research - Category: Drugs & Pharmacology Source Type: research
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