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Dengue outbreak kills 300 in Sri Lanka, hospitals at limit

COLOMBO (Reuters) - An outbreak of dengue virus has killed around 300 people so far this year in Sri Lanka and hospitals are stretched to capacity, health officials said on Monday.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news

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Discussion Leg pain in children has a broad differential diagnosis and includes more innocuous problems such as growing pains and transient synovitis but also more serious problems including neurological diseases or malignancy. Occult or self-limited trauma are also common causes. A review can be found here. Limping can be painful or painless and has its own differential diagnosis which can overlap with leg pain. A differential diagnosis for limping can be found here. Muscle weakness also has its’ own differential diagnosis which can be found here. Learning Point Benign acute childhood myositis (BACM) has other names...
Source: PediatricEducation.org - Category: Pediatrics Authors: Tags: Uncategorized Source Type: news
Dengue (DV), chikungunya (CV) and Zika virus (ZV) infections are rapidly expanding across countries and diagnosed in returned travelers who represent epidemiological sentinels. French Territories of America (FTA) such as Guadeloupe and Martinique are highly touristic places and have experienced three consecutive outbreaks by such viruses in the last decade.
Source: International Journal of Infectious Diseases - Category: Infectious Diseases Authors: Source Type: research
AbstractAsia and its Hindu Kush Himalayan (HKH) region is particularly vulnerable to environmental change, especially climate and land use changes further influenced by rapid population growth, high level of poverty and unsustainable development. Asia has been a hotspot of dengue fever and chikungunya mainly due to its dense human population, unplanned urbanization and poverty. In an urban cycle, dengue virus (DENV) and chikungunya virus (CHIKV) are transmitted byAedes aegypti andAe. albopictus mosquitoes which are also competent vectors of Zika virus (ZIKV). Over the last decade, DENV and CHIKV transmissions byAe. aegypti...
Source: Infectious Diseases of Poverty - Category: Infectious Diseases Source Type: research
Guillain-Barr é syndrome (GBS), an acute, immune- mediated polyradiculoneuropathy, typically occurs in response to minor viral and bacterial infections. Associations between this syndrome and previous arboviral infection, such as dengue (DENV), chikungunya (CHIKV) or Zika virus (ZIKV), have been reported in some studies [1,2]. GBS usually manifests as generalized weakness and areflexia, accompanied by sensory and autonomic disturbances [3]. Mild neurologic syndromes associated with ZIKV infection have previously been described, characterized by short-term isolated sensory disturbances [4,5].
Source: Journal of the Neurological Sciences - Category: Neurology Authors: Tags: Letter to the Editor Source Type: research
(Emory Health Sciences) Identifying dengue fever 'hot spots' can provide a predictive map for outbreaks of chikungunya and Zika -- two other viral diseases that, along with dengue, are spread by the Aedes aegypti mosquito.
Source: EurekAlert! - Infectious and Emerging Diseases - Category: Infectious Diseases Source Type: news
Abstract The resistance status of Selangor Aedes aegypti (Linnaeus) larvae against four major groups of insecticides (i.e., organochlorines, carbamates, organophosphates and pyrethroids) was investigated. Aedes aegypti were susceptible against temephos (organophosphate), although resistance (RR50 = 0.21 - 2.64) may be developing. The insecticides susceptibility status of Ae. aegypti larvae were found heterogeneous among the different study sites. Results showed that Ae. aegypti larvae from Klang, Sabak Bernam and Sepang were susceptible against all insecticides tested. However, other study sites exhibited low ...
Source: Acta Tropica - Category: Infectious Diseases Authors: Tags: Acta Trop Source Type: research
This article describes the laboratory based surveillance system in Suriname and the incidence of confirmed cases of ZIKV infection according to sex, age, and spatial and temporal distribution Methods General practitioners and public health centers located in different districts of Suriname were asked to send blood samples from suspicious cases to Academic Hospital for molecular diagnosis of Zika virus infection. In particular, in cases involving pregnant women, samples were screened for free upon request. Viral RNA was extracted from blood and urine samples using a RNeasy Mini Kit (Qiagen, Hilden, Germany). An in-house ...
Source: PLOS Currents Outbreaks - Category: Epidemiology Authors: Source Type: research
by John H. Huber, Marissa L. Childs, Jamie M. Caldwell, Erin A. Mordecai Dengue, chikungunya, and Zika virus epidemics transmitted byAedes aegypti mosquitoes have recently (re)emerged and spread throughout the Americas, Southeast Asia, the Pacific Islands, and elsewhere. Understanding how environmental conditions affect epidemic dynamics is critical for predicting and responding to the geographic and seasonal spread of disease. Specifically, we lack a mechanistic understanding of how seasonal variation in temperature affects epidemic magnitude and duration. Here, we develop a dynamic disease transmission model for dengue ...
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
Abstract Social and demographic changes over the past 50 years resulted in important outbreaks of arboviruses such as dengue virus (DENV) and Zika virus (ZIKV) all over the world. Despite such potential threat, no approved drugs or fully protective vaccines are available to counteract DENV and ZIKV spreading. The development of "broad spectrum" antivirals (BSAs) targeting common components of multiple viruses, can be a more effective strategy to limit the rapid rise of emerging viral pathogens than the classic "one-bug/one-drug" approach. Starting from previously identified multitarget DENV inh...
Source: ChemMedChem - Category: Chemistry Authors: Tags: ChemMedChem Source Type: research
Songjiao Wen, Dehong Ma, Yao Lin, Lihua Li, Shan Hong, Xiaoman Li, Xiaodan Wang, Juemin Xi, Lijuan Qiu, Yue Pan, Junying Chen, Xiyun Shan, Qiangming Sun
Source: Frontiers in cellular and infection microbiology - Category: Microbiology Source Type: research
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