Biomaterials, substitutes, and tissue engineering in bone repair: current and future concepts

AbstractBone is a complex, constantly changing organ comprised of mineralized hard tissue. This important structural component of vertebrate ’s body serves a variety of functions. Healthy bone system is essential for lifelong execution of these functions. Millions of people worldwide suffer from bone defects due to various reasons, including trauma, tumor, bone diseases, congenital defects, and aging. These defects are increasingly bec oming the majority of the clinical cases in orthopedics. For all the aforementioned cases in which the normal process of bone regeneration is either impaired or simply insufficient, there are currently a number of treatment methods available which can be used either alone or in combination for the e nhancement of bone healing and regeneration. Accordingly, bone repair has been the focus of many research activities related to clinical therapies. The traditional bone repair procedure widely used in current era involves the use of bone-grafting methods such as autografts, allografts, and xenograft s; however, these methods are associated with number of limitations. Therefore, to overcome these problems, tissue engineering as a new and developing option had been introduced recently. In order to provide ideal bone substitutes, a wide range of biomaterials and synthetic bone substitutes are avai lable depending on the goal, each has advantages and disadvantages. The combined use of different bone substitutes together with healing promotive fact...
Source: Comparative Clinical Pathology - Category: Pathology Source Type: research

Related Links:

Publication date: Available online 21 November 2019Source: Journal of Cancer PolicyAuthor(s): Brandon Maser, Lisa M. Force, Paola Friedrich, Federico Antillon, Ramandeep S. Arora, Cristian A. Herrera, Carlos Rodriguez-Galindo, Rifat Atun, Avram DenburgAbstractTo help understand how health systems and sociopolitical contexts intersect with and impact the performance of childhood cancer care in low- and middle-income countries (LMICs), we have developed a systems-level framework for analyzing the performance of LMIC childhood cancer programs within their health system contexts: The Paediatric Oncology System Integration Tool...
Source: Journal of Cancer Policy - Category: Cancer & Oncology Source Type: research
Future Oncology, Ahead of Print.
Source: Future Oncology - Category: Cancer & Oncology Authors: Source Type: research
Cancer Biotherapy and Radiopharmaceuticals, Ahead of Print.
Source: Cancer Biotherapy and Radiopharmaceuticals - Category: Cancer & Oncology Authors: Source Type: research
Cancer Biotherapy and Radiopharmaceuticals, Ahead of Print.
Source: Cancer Biotherapy and Radiopharmaceuticals - Category: Cancer & Oncology Authors: Source Type: research
Date: Thursday, 12 12, 2019; Speaker: Julie Blendy , Ph.D. Professor of Pharmacology, Perelman School of Medicine, University of Pennsylvania; Building: Building 40; 1201/1203
Source: NIH Calendar of Events - Category: American Health Source Type: events
Date: Thursday, 12 19, 2019; Speaker: Cristine Delnevo, Ph.D., M.P.H., F.A.A.H.B., Director, Center for Tobacco Studies, Society and Policy Rutgers School of Public Health; Nir Eyal, D.Phil, Director, Center for Population-Level Bioethics (CPLB), Society and Policy Rutgers School of Public Health; https://epi.grants.cancer.gov/events/enrich-forum/
Source: NIH Calendar of Events - Category: American Health Source Type: events
Date: Monday, 01 27, 2020; Speaker: Lisa Ingraham, Ph.D., University of California, San Francisco; Porter Neuroscience Bldg, 35a; G620-640; Videocast Event
Source: NIH Calendar of Events - Category: American Health Source Type: events
Date: Friday, 11 22, 2019; Speaker: various; Building 38; Conference room B, second floor
Source: NIH Calendar of Events - Category: American Health Source Type: events
Date: Friday, 11 22, 2019; Speaker: Nicola Santoro, MD, PhD, Assistant Professor of Pediatrics (Endocrinology), Yale School of Medicine; Building 10 CRC; FAES 1&2
Source: NIH Calendar of Events - Category: American Health Source Type: events
Date: Monday, 11 25, 2019; Speaker: Eugene M. Oltz , Chair of the Department of Microbial Infection and Immunity , College of Medicine – The Ohio State University; 37; 6041
Source: NIH Calendar of Events - Category: American Health Source Type: events
More News: Bone Graft | Gastroschisis Repair | Gene Therapy | Genetics | Orthopaedics | Pathology | Stem Cell Therapy | Stem Cells