Free flap reconstruction for patients aged 85 years and over with head and neck cancer: clinical considerations for comprehensive care

Publication date: Available online 21 July 2017 Source:British Journal of Oral and Maxillofacial Surgery Author(s): X.F. Chen, Y.M. Chen, S. Gokavarapu, Q.C. Shen, T. Ji We aimed to identify and evaluate the clinical challenges involved in microvascular flap reconstructions of defects caused by resection of head and neck cancer among patients aged 85 and over. We designed a retrospective study of patients who were treated in the head and neck department of a tertiary referral centre from 2005 to 2015, and all patients aged 85 years and over who had reconstructions with microvascular flaps for head and neck cancer were entered into the study. A total of 24 patients fulfilled the criteria, of whom 15 were men and nine were women. The median (range) duration of stay in hospital was 23 (14-59) days. Eighteen patients had an American Society of Anesthesiologists (ASA) score grade II and six patients grade III. The median (range) operating time was 420 (310-705)minutes, and operative blood loss 550 (200-1500)ml. Sixteen patients had prophylactic tracheostomies, nine of whom developed postoperative surgical complications, seven associated with the tracheostomy (p=0.005). Resections of head and neck cancer and microvascular reconstructions in patients aged 85 and over are associated with a high incidence of postoperative complications. Medical complications tend to be associated with the tracheostomy while surgical complications are potentially associated with the ASA score. Althoug...
Source: British Journal of Oral and Maxillofacial Surgery - Category: ENT & OMF Source Type: research

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AbstractIn a country such as India, popularly known for its rich diversity and traditions, chewing tobacco and its many other forms is a commonly practised entity. The resultant of this leads to oral submucous fibrosis (OSMF) which causes permanent morbidity in the form of trismus and also can lead to potential possibility of oral cancer. Intra oral injections of steroids such as hyaluronidase and placentrex have been postulated by many studies. But this study was done to evaluate the efficacy of both these commonly used treatment modalities. A 1  year hospital based study was performed over 30 patients diagnosed to b...
Source: Indian Journal of Otolaryngology and Head and Neck Surgery - Category: ENT & OMF Source Type: research
Compartmental surgery and primary reconstruction with microvascular free flaps represent the gold-standard in the treatment of oral tongue squamous cell carcinoma (OTSCC). However, there are still unclear clinical features that negatively affect the outcomes. This retrospective study included 80 consecutive patients with OTSCC who underwent compartmental surgery and primary reconstruction by free flap. The oncologic outcomes, the reliability of the 8th edition American Joint Committee on Cancer (AJCC) staging system and the prognostic factors were evaluated. Fifty-nine males and 21 females (mean age 57.8 years, range 27&nd...
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
Publication date: Available online 11 July 2020Source: British Journal of Oral and Maxillofacial SurgeryAuthor(s): A. Dahill, H. Al-Nakisbandi, K.B. Cunningham, G.M. Humphris, D. Lowe, S.N. Rogers
Source: British Journal of Oral and Maxillofacial Surgery - Category: ENT & OMF Source Type: research
For decades, hyperbaric oxygen (HBO) has often been part of the treatment of osteoradionecrosis (ORN), despite controversy in the literature about its efficacy. An online survey was conducted to investigate the use of HBO in the treatment of ORN by Dutch oral and maxillofacial surgeons and to assess their perception of its efficacy. Of the 53 Dutch oral and maxillofacial surgery units contacted, 49 (92%) replied. Thirty-five were not head and neck cancer (HNC) units or preferred partner (PP-HNC) units recognized by the Dutch Head and Neck Association.
Source: International Journal of Oral and Maxillofacial Surgery - Category: ENT & OMF Authors: Tags: International News Source Type: research
Loneliness is associated with a poor quality of life, mental illness, poor physical health, and premature mortality. Patients with head and neck cancer (HNC) are at risk of loneliness because of the effects of the disease and its treatment on important social interactive functions such as appearance, speech, facial expression, and eating. Patients treated for primary squamous cell HNC between January 2015 and December 2016 were surveyed in early 2019 using the University of Washington quality of life questionnaire version 4, the Cancer-related Loneliness Assessment Tool (C-LAT), and four nationally recommended indicator questions.
Source: The British Journal of Oral and Maxillofacial Surgery - Category: ENT & OMF Authors: Source Type: research
AbstractCoronavirus disease 2019 commonly designated as COVID-19 has been declared by World health Organisation (WHO) as a pandemic on 11 March 2020. ‘Lock down’ is found to be the only effective method to control this outbreak and due to the contagious nature of this disease most of the hospitals have stopped elective interventions. Cancer is a second leading cause of death globally and the bystander victims in this scenario are the patients with suspected and proven cancer. Head and neck cancer has a survival rate of 40% to 50% after definitive therapy and the delay in treatment for even 1-2 months may lead t...
Source: Journal of Maxillofacial and Oral Surgery - Category: ENT & OMF Source Type: research
AbstractBackgroundDocetaxel, cisplatin, and 5-fluorouracil (TPF) induction chemotherapy (ICT) is a treatment option for locally advanced unresectable head and neck squamous cell carcinoma (LA-HNSCC). However, patients with advanced age, or renal, cardiac or neurogenic dysfunction are ineligible for ICT-TPF.MethodsWe retrospectively assessed 24 unresectable LA-HNSCC patients who received paclitaxel, carboplatin and cetuximab (PCE) as ICT at the Shizuoka Cancer Center between April 2013 and October 2018.ResultsPatient characteristics were as follows: median age, 72  years (range 60–81); 0, 1, and 2 performance sta...
Source: International Journal of Clinical Oncology - Category: Cancer & Oncology Source Type: research
CONCLUSION: Conventional honey might constitute a highly promising natural product against OM attracting much scientific interest thanks to its easy accessibility and low financial cost. Hence, the lack of studies with high evidence requires further advanced research to enhance the existing knowledge about the potential value of honey in radiation induced OM in H-N cancer patients. PMID: 32646360 [PubMed - as supplied by publisher]
Source: Reviews on Recent Clinical Trials - Category: Cancer & Oncology Authors: Tags: Rev Recent Clin Trials Source Type: research
Publication date: Available online 7 July 2020Source: British Journal of Oral and Maxillofacial SurgeryAuthor(s): Damian Broderick, Derek Lowe, Anastasios Kanatas, Simon N Rogers
Source: British Journal of Oral and Maxillofacial Surgery - Category: ENT & OMF Source Type: research
This study aimed to clarify the risk factors of head and neck cancer (HNC) mortality, relative to those of all-cause and all-cancer mortalities, using the Korean National Health Insurance Service-Health Screening Cohort (NHIS-HEALS) data set. Data from 238 HNC deaths, 14,769 all-cancer deaths, and 38,086 all-cause deaths were extracted during a median follow-up period of 9.5 years. Baseline characteristics were assessed via chi-square tests, t tests, and multivariable logistic regression. HNC mortality was found to be positively associated with male sex, past and current smoking habits, moderate-to-heavy alcohol consumptio...
Source: Journal of oral science - Category: Dentistry Tags: J Oral Sci Source Type: research
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