Inhibition of Necroptosis Attenuates Kidney Inflammation and Interstitial Fibrosis Induced By Unilateral Ureteral Obstruction.

CONCLUSION: These findings suggest that the participation of necroptosis in UUO is partly demonstrated. And necroptosis inhibition may have a potential role in the treatment of diseases with increased inflammatory response and interstitial fibrosis in renal.
PMID: 28723681 [PubMed - as supplied by publisher]

Source: American Journal of Nephrology - July 20, 2017 Category: Urology & Nephrology Authors: Xiao X, Du C, Yan Z, Shi Y, Duan H, Ren Y Tags: Am J Nephrol Source Type: research