Can cerebellin and renalase measurements contribute to the elimination of false positive results in pheochromocytoma and paraganglioma diagnoses?

Tumors of the sympathetic nervous system, both pheochromocytoma and paraganglioma release norepinephrine. While there is no catecholamine (norepinephrine; epinephrine) secretion in some paraganglioma cases, epinephrine is secreted in addition to norepinephrine in some pheochromocytoma cases [1]. Excessive norepinephrine leads to high blood pressure and excessive epinephrine to tachyarrhythmia [2]. Metanephrine and normetanephrine measurements are conducted for the biochemical diagnosis of pheochromocytoma and paraganglioma.

Source: Medical Hypotheses - July 20, 2017 Category: Biomedical Science Authors: Suleyman Aydin Source Type: research