In vitro activity of daptomycin combinations with rifampicin, gentamicin, fosfomycin and fusidic acid against MRSA strains

Conclusion The combination of daptomycin with fosfomycin may be a promising alternative therapy of MRSA infections.
Source: Journal of Global Antimicrobial Resistance - Category: Infectious Diseases Source Type: research

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(University of Michigan) Recycled and aged human urine can be used as a fertilizer with low risks of transferring antibiotic resistant DNA to the environment, according to new research from the University of Michigan.
Source: EurekAlert! - Biology - Category: Biology Source Type: news
In this study, Ca-LTA Zeolite-diatomite-based adsorbents with purified diatomite loading rates of 15, 20 and 25 wt% are investigated by physicochemical, thermal and antibacterial characterizations. X-ray diffraction and FTIR spectroscopy analyses show that the purified diatomite is homogeneously dispersed into the Ca-LTA zeolite and that the zeolite crystalline structure is preserved. All analyses indicate that porous volumes, specific surface areas and initial water adsorption rates are affected by the mesoporosity nature of diatomite. Based on the water TPD profiles, the variation of the activation energy (Ea) and e...
Source: Colloids and Interface Science Communications - Category: Nanotechnology Source Type: research
Publication date: Available online 20 January 2020Source: LWTAuthor(s): Haiying Cui, Chenghui Zhang, Changzhu Li, Lin LinAbstractIn recent years, studies have found that in addition to nosocomial infections, methicillin-resistant Staphylococcus aureus (MRSA) can even cause community-associated infections, and MRSA spreads through food and animal that produce products in the community. In addition, MRSA can colonize the surface of food and food container and form biofilms by secreting extracellular polymers, leading to cross-infection. Cardamom essential oil has been found to be highly active against MRSA. Therefore, this s...
Source: LWT Food Science and Technology - Category: Food Science Source Type: research
Publication date: Available online 20 January 2020Source: Methods in MicrobiologyAuthor(s): Maria M. Plummer, Charles S. PaviaAbstractImmunoassay detection of specific antigens and host-produced antibodies directed against such antigens constitute two of the most widely used and successful methods for diagnosing infectious diseases and many of the non-infectious autoimmune disorders. We will be reviewing some of the epidemiology, microbiology, and clinical aspects of selected organisms and discuss their diagnosis by describing some of the major antigen detection systems and serologic techniques available to health care pro...
Source: Methods in Microbiology - Category: Microbiology Source Type: research
Publication date: April 2020Source: Micron, Volume 131Author(s): Samuel R. Greenfield, Scott W. Tighe, Yu Bai, David S. Goerlitz, Michele Von Turkovich, Douglas J. Taatjes, Julie A. Dragon, Sarah Stewart JohnsonAbstractThe extremely cold and arid conditions of Antarctica make it uniquely positioned to investigate fundamental questions regarding the persistence of life in extreme environments. Within the McMurdo Dry Valleys and surrounding mountain ranges are multiple ancient relict lakes, paleolakes, with lacustrine deposits spanning from thousands to millions of years in age. Here we present data from light microscopy, sc...
Source: Micron - Category: Biology Source Type: research
In this study, three 3D-supra-molecular coordination compounds namely, [Ag2L(NO3)2]n (1), {[Ag2L][PF6]2}n (2) and [AgLBr]n (3) (L =1,1’-(1,5-pentadienyl)bis-(1,3-dihydro-3-methyl-1H-imidazole-2-thione)) have been synthesized and fully characterized via a single crystal X-ray diffraction, powder X-ray diffraction (PXRD), elemental analysis (CHN), FT-IR spectra and thermo gravimetric analysis (TGA). Structural analysis revealed that the counter ions have a notable impact in directing the conformation and coordination mode of ligand, but they have no effect on the structural dimension of the polymers. Furthermore, by in...
Source: Inorganica Chimica Acta - Category: Chemistry Source Type: research
In this study, three tribenzoporphyrazines with dendrimeric peripheral substituents were subjected to in vitro antimicrobial photocytotoxicity study. One new magnesium(II) tribenzoporphyrazine with peripheral 3,5-bis(3,5-dimethoxybenzyloxy)benzylsulfanyl substituents was synthesized and subjected to physicochemical characterization using NMR, UV–Vis, and mass spectrometry techniques. In photochemical studies this molecule revealed moderate singlet oxygen generation ability (ΦΔDMF = 0.12, ΦΔDMSO = 0.13). The other two magnesium(II) tribenzoporphyrazines applied in the biological study were ...
Source: Journal of Photochemistry and Photobiology B: Biology - Category: Speech-Language Pathology Source Type: research
I came across an article inForbes discussing beauty and wellness trends for 2020 (see:9 Beauty And Wellness Trend Predictions For 2020 And Beyond). Included in the article was the graphic shown below that categorizes the global wellness economy for 2017 into various segments. All of this raised the question in my mind about how health systems can pursue a portion of this huge wellness market without straying too far from their roots. First, take a look at the graph below.I believe that it would be relatively easy for health systems to become more engaged in three segments of the global wellness industry as shown above...
Source: Lab Soft News - Category: Laboratory Medicine Authors: Tags: Health Wearable Healthcare Delivery Healthcare Innovations Medical Consumerism Population Health Public Health Quality of Care Source Type: blogs
Conclusions These findings indicate that linezolid has an excellent activity against clinical drug resistant Gram-positive isolates in Iran. Constant monitoring and surveillance of linezolid MIC distribution allows the researchers to assess and detect gradual upward MIC drifts.
Source: Journal of Global Antimicrobial Resistance - Category: Infectious Diseases Source Type: research
Conclusion From our findings we concluded that the rate of isolation of MRSA among all the strains of S. aureus isolated from clinical samples was very high. However, none of the MRSA strains were found to be vancomycin intermediate-sensitive or vancomycin-resistant.
Source: Antimicrobial Resistance and Infection Control - Category: Infectious Diseases Source Type: research
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