Linezolid activity against clinical Gram-positive cocci with advanced antimicrobial drug resistance in Iran

Conclusions These findings indicate that linezolid has an excellent activity against clinical drug resistant Gram-positive isolates in Iran. Constant monitoring and surveillance of linezolid MIC distribution allows the researchers to assess and detect gradual upward MIC drifts.
Source: Journal of Global Antimicrobial Resistance - Category: Infectious Diseases Source Type: research

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In conclusion no ceftriaxone resistance has been found in Nuuk to date. Continued easy access to diagnostics and treatment combined with increased and more systematic surveillance of antimicrobial susceptibility in Nuuk is recommended. Further, it is advisable to investigate the possibilities for intermittent sampling in Greenland outside of Nuuk, if obstacles in relation to sending sampling material to Nuuk can be bypassed. PMID: 31809690 [PubMed - in process]
Source: International Journal of Circumpolar Health - Category: International Medicine & Public Health Tags: Int J Circumpolar Health Source Type: research
Conclusion: The results suggest that pre- and post-treatment with EGCG may be effective in protecting spinal cord from IRI. PMID: 31809244 [PubMed - as supplied by publisher]
Source: Journal of Spinal Cord Medicine - Category: Orthopaedics Tags: J Spinal Cord Med Source Type: research
Authors: Severyn CJ, Brewster R, Andermann TM Abstract Growing evidence suggests that human microbiota likely influence diverse processes including hematopoiesis, chemotherapy metabolism, and efficacy, as well as overall survival in patients with hematologic malignancies and other cancers. Both host genetic susceptibility and host-microbiota interactions may impact cancer risk and response to treatment; however, microbiota have the potential to be uniquely modifiable and accessible targets for treatment. Here, we focus on strategies to modify microbiota composition and function in patients with cancer. First, we ev...
Source: Hematology ASH Education Program - Category: Hematology Tags: Hematology Am Soc Hematol Educ Program Source Type: research
Conclusions: Given the significant risk of Cryptococcus species for susceptible humans, mainly HIV-infected patients, it seems quite necessary to adopt concrete preventive strategies to pinpoint the environmental habitats of this yeast.
Source: Journal of Medical Mycology - Category: Biology Source Type: research
Publication date: February 2020Source: Phytochemistry Letters, Volume 35Author(s): Allan Patrick G. Macabeo, Allaine Jean C. Cruz, Abolfazl Narmani, Mahdi Arzanlou, Asadollah Babai-Ahari, Luis Agustin E. Pilapil, Katherine Yasmin M. Garcia, Volker Huch, Marc StadlerAbstractTwo new α-pyrone derivatives, udagawanones A (1) and B (2), along with the known compounds (Z)-4-hydroxy-3-(3-hydroxy-3-methylbut-1-en-1-yl)benzoic acid (3), isosclerone (4), cyclo-(L-Leu-L-Pro) (5), and cyclo-(L-Pro-L-Tyr) (6), were isolated from cultures of the endophyte Neurospora udagawae. Their structures were elucidated by extensive spectrosc...
Source: Phytochemistry Letters - Category: Chemistry Source Type: research
Publication date: Available online 6 December 2019Source: Journal of Photochemistry and Photobiology B: BiologyAuthor(s): Sai Kumar Tammina, Yang Wan, Yan Yan Li, Yaling YangAbstractA simple and one-step microwave digestion method was utilized to synthesize the highly photoluminescent glucosamine derived nitrogen and zinc doped carbon dots (N, Zn-CDs) with a bluish-green luminescence property. The synthesized N, Zn-CDs inherited a good photoluminescence property with a quantum yield of 74% and which were characterized with XPS, XRD, TEM, FT-IR, UV–Vis, and fluorescence spectrometry. More importantly N, Zn-CDs served ...
Source: Journal of Photochemistry and Photobiology B: Biology - Category: Speech-Language Pathology Source Type: research
Conclusions: AEs were common, but not more frequent or severe among MDR-TB/HIV co-infected participants receiving concurrent antiretroviral therapy. Given the favorable treatment outcomes associated with concurrent treatment, antiretroviral therapy initiation should not be delayed in MDR-TB patients with HIV-coinfection.
Source: JAIDS Journal of Acquired Immune Deficiency Syndromes - Category: Infectious Diseases Tags: Clinical Science Source Type: research
Publication date: Available online 5 December 2019Source: Materials LettersAuthor(s): Sheena Raina, Anupma Thakur, Aditi Sharma, D. Pooja, Anu Priya MinhasAbstractThe present was the first report on the synthesis of Carbon dots (CDs) using the acetone leaf extract of Cannabis sativa, an abundant weed plant as a sole carbon precursor. The obtained ∼5 nm spherical CD particles (exhibiting 13% absolute quantum yield) were further to synthesize silver@CDs (Ag@CDs). CDs and Ag@CDs characterization revealed characteristic functional groups attributing to the aromatic, carboxylated and hydroxylated moieties. Ether and acetone...
Source: Materials Letters - Category: Materials Science Source Type: research
Publication date: Available online 5 December 2019Source: Plant ScienceAuthor(s): Jing Lin, Zejun Lan, Wenhuan Hou, Chunyan Yang, Dagang Wang, Mengchen Zhang, Haijian ZhiAbstractSoybean mosaic virus (SMV) is a major pathogen causing yield loss. Developing soybean plants tolerant or resistant to SMV is important for mitigating the adverse effects of the viral infection. However, most studies have focused on the resistance to normal SMV strains. Thus, investigations of the resistance or tolerance to the novel recombinant SMV strain have been limited. To address the threat of the recombinant SMV, two soybean parent genotypes ...
Source: Plant Science - Category: Biology Source Type: research
Publication date: Available online 5 December 2019Source: Carbohydrate PolymersAuthor(s): Tingsheng Yan, Jinmei He, Rongmei Liu, Zhonghua Liu, Jinju ChengAbstractCombination therapy provides an efficient way to overcome the potential multidrug resistance and enhance anticancer efficacy. In this work, a biodegradable pH-responsive hollow mesoporous silica nanoparticle (HMSN-GM-CS-FA) was developed for co-delivery of pheophorbide a (PA) and doxorubicin (DOX). This drug delivery system possessed controlled particle size and larger inner hollow core, which endowed the nanoparticle with excellent encapsulation capacities.The up...
Source: Carbohydrate Polymers - Category: Biomedical Science Source Type: research
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