High-Throughput Analysis of Ovarian Cycle Disruption by Mixtures of Aromatase Inhibitors

Conclusions:
These results demonstrate the possibility to predict large-scale mixture effects for endocrine disrupters with a predictive toxicology approach that is suitable for high-throughput ranking and risk assessment. The size of the effects predicted is consistent with an increased risk of infertility in women from everyday exposures to our chemical environment. https://doi.org/10.1289/EHP742

Received: 30 June 2016
Revised: 07 December 2016
Accepted: 24 February 2017
Published: 19 July 2017
Address correspondence to F.Y. Bois, INERIS, DRC/VIVA, Parc ALATA, BP 2, 60550 Verneuil en Halatte, France. Telephone: [phone]; Email: [e-mail]
Supplemental Material is available online (https://doi.org/10.1289/EHP742).
The authors declare they have no actual or potential competing financial interests.
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Source: EHP Research - July 19, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research