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CU Boulder discovery could lead to better results for patients undergoing radiation

(University of Colorado at Boulder) A new study involving CU Boulder shows why some cells treated with radiation therapy for cancer leak chemical signals and damage unexposed healthy cells, findings that could lead to new medications that patients could take prior to radiation.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news

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Authors: Oweida AJ, Phan A, Vancourt B, Robin T, Hararah MK, Bhatia S, Milner D, Lennon S, Pike L, Raben D, Haugen BR, Pozdeyev N, Schweppe RE, Karam SD Abstract Anaplastic thyroid cancer is an aggressive and highly lethal disease with poor outcomes and resistance to therapy. Despite multimodality treatment including radiation therapy and chemotherapy, response rates remain below 15% with a median time to progression of less than 3 months. Recent advances in radiotherapy delivery and gene-expression profiling may help guide patient selection for personalized therapy. The purpose of this study was to characterize th...
Source: Thyroid : official journal of the American Thyroid Association - Category: Endocrinology Tags: Thyroid Source Type: research
CONCLUSION: CMT was associated with superior survival outcomes compared to monotherapy. We observed no survival difference between radiation modalities in CMT, which highlights the effectiveness of a more focused treatment like brachytherapy. PMID: 29770620 [PubMed - as supplied by publisher]
Source: Journal of Gynecologic Oncology - Category: OBGYN Tags: J Gynecol Oncol Source Type: research
On Thursday, the Food and Drug Administration approved the first drug designed to prevent chronic migraine headaches. Aimovig, made by Amgen and Novartis, is a monthly, self-administered injection that blocks a molecule involved in migraine attacks. Over the course of three clinical trials, the drug was successful at reducing the frequency of migraines for chronic sufferers. It is expected to be available in as soon as a week and will cost $575 per month, though out-of-pocket costs will vary depending on insurance. This is the story of Susan Giordano, 58, whose chronic migraines have nearly ceased after taking a monthly s...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized healthytime medicine onetime Source Type: news
CONCLUSIONS: IGRT based on soft tissue match provides a noninvasive convenient method for daily localization and is accurate within treatment uncertainty for the majority of cases. PMID: 29774779 [PubMed - as supplied by publisher]
Source: Acta Oncologica - Category: Cancer & Oncology Authors: Tags: Acta Oncol Source Type: research
Publication date: July–August 2018 Source:Reports of Practical Oncology & Radiotherapy, Volume 23, Issue 4 Author(s): Beatriz Sánchez-Nieto, Maria Romero-Expósito, José Antonio Terrón, Leticia Irazola, Marta Paiusco, Elisabetta Cagni, Caterina Ghetti, Silvano Filice, Francisco Sánchez-Doblado The aim of this work was to estimate peripheral neutron and photon doses associated with the conventional 3D conformal radiotherapy techniques in comparison to modern ones such as Intensity modulated radiation therapy and volumetric modulated arc therapy. Assessment in terms of second canc...
Source: Reports of Practical Oncology and Radiotherapy - Category: Cancer & Oncology Source Type: research
Varian Medical (NYSE:VAR) said today it inked a software technology training and education cooperation agreement with the Brazil Ministry of Health and seven universities and science and tech institutes in the country. The Palo Alto, Calif.-based medical device maker said the agreement is part of its strategy of partnering with the Ministry of Health to increase quality and access to radiotherapy treatments in Brazil and across Latin America. Varian said that the list of participating institutions includes the Universidade Federal de São Paulo, Universidade Federal de Pernambuco, Instituto Nacional de Telecomun...
Source: Mass Device - Category: Medical Devices Authors: Tags: Business/Financial News Oncology Varian Medical Systems Source Type: news
Condition:   Cervical Cancer Interventions:   Drug: Nivolumab induction;   Drug: Cisplatin;   Radiation: Radiation;   Drug: Nivolumab with chemoradiation;   Drug: Nivolumab maintenance Sponsors:   Don Dizon;   Rhode Island Hospital;   The Miriam Hospital;   Women and Infants Hospital of Rhode Island;   Bristol-Myers Squibb Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
AbstractPurpose of ReviewOur aim is to review the steps of diagnosis and management of gynecomastia with a special focus on treatment of gynecomastia associated with androgen deprivation therapy for prostate cancer.Recent FindingsRecent studies investigating tamoxifen and radiation therapy for both therapy and prophylaxis of bicalutamide-induced gynecomastia are reviewed.SummaryGynecomastia is a common clinical problem, affecting between one and two thirds of middle-aged men. Diagnosis is typically made by history and physical exam. Common causes include chronic medical conditions and medications; however, unexplained gyne...
Source: Current Urology Reports - Category: Urology & Nephrology Source Type: research
I. S. Dayes, S. Parpia, J. Gilbert, J. A. Julian, I. R. Davis, M. N. Levine and J. Sathya
Source: The Journal of Urology - Category: Urology & Nephrology Authors: Tags: Urological Survey Source Type: research
This study was to evaluate the correlation between the change of apurinic/apyrimidinic endonuclease 1/redox factor-1 (Ape1/Ref-1), intercellular adhesion molecules 1 (ICAM-1) and interleukin-17A (IL-17A) before and after radiotherapy and radiation pneumonitis for local advanced non-small cell lung cancer (NSCLC) patients with concurrent chemoradiotherapy. Methods NSCLC patients (68 cases) were treated with concurrent radiotherapy and chemotherapy, every patient ’s normal tissue were controlled with a same radation dose. 68 local advanced NSCLC patients with concurrent chemoradiotherapy were detected the levels of Ape...
Source: Chinese Journal of Lung Cancer - Category: Cancer & Oncology Source Type: research
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