Onconephrology: New mouse model of clear cell renal cell carcinoma

Nature Reviews Nephrology 13, 444 (2017).
doi:10.1038/nrneph.2017.89

Author: Ellen F. Carney
A new autochthonous mouse model of clear cell renal cell carcinoma (ccRCC) could be used to investigate ccRCC biology and test new therapies. Combined deletion of Vhl, Trp53 and Rb1 in renal epithelial cells induced the development of ccRCC tumours that arose

Source: Nature Reviews Nephrology - June 12, 2017 Category: Urology & Nephrology Authors: Ellen F. Carney Tags: Research Highlight Source Type: research