Kent hairdresser with acromegaly could not stop growing

Lauren Bates, 26, from New Romney, Kent, was diagnosed with acromegaly. The rare condition was made famous by Richard Kiel, who played Jaws in The Spy Who Loved Me.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news

Related Links:

CONCLUSIONS: We will focus on the issues regarding the measurement and interpretation of IGF-I concentrations in the management of acromegaly patients. PMID: 30311754 [PubMed - as supplied by publisher]
Source: Minerva Endocrinologica - Category: Endocrinology Tags: Minerva Endocrinol Source Type: research
Authors: Yuen KC, Popovic V Abstract Previous studies have implicated the growth hormone (GH)/IGF-I axis as an important mediator of cancer risk in humans and animals. Evidence supporting this notion is derived from animal studies, epidemiological observations, patients with acromegaly and from therapeutic manipulation of GH and IGF-I actions. Therefore, the use of GH therapy in patients with a history of malignancy raises hypothetical safety concerns. Reassuringly, GH therapy in childhood cancer survivors has not been confirmed to increase the cancer risk. Conversely, the risk of occurrence of a second neoplasm ma...
Source: Expert Review of Endocrinology and Metabolism - Category: Endocrinology Tags: Expert Rev Endocrinol Metab Source Type: research
Authors: Claessen KM, Pereira AM, Biermasz NR Abstract Acromegaly patients suffer from pathologically high growth hormone (GH) and IGF-1 levels that in 99% of cases is due to a GH-producing pituitary adenoma. During active disease, GH excess is associated with a number of pathological conditions, such as hypertension, hypertrophic cardiomyopathy, sleep apnea, arthropathy, vertebral fractures and insulin resistance. After adequate treatment in the form of transsphenoidal surgery, radiotherapy, medical treatment or by a combination of these treatment modalities, several comorbid conditions improve considerably. Howev...
Source: Expert Review of Endocrinology and Metabolism - Category: Endocrinology Tags: Expert Rev Endocrinol Metab Source Type: research
Publication date: Available online 12 October 2018Source: Academic RadiologyAuthor(s): Zongming Wang, Zhigang Mao, Xiangsong Zhang, Dongsheng He, Xin Wang, Qiu Du, Zheng Xiao, Diming Zhu, Yonghong Zhu, Haijun WangRationale and ObjectivesIt is clinically essential, but sometimes challenging, to distinguish pituitary tissue from pituitary adenomas (PAs). It is helpful to avoid damage of pituitary tissue during management. We evaluated the ability of 13N-ammonia positron emission tomography (PET)/computed tomography (CT) to locate and distinguish pituitary tissue from PAs.Materials and MethodsForty-eight patients (four with p...
Source: Academic Radiology - Category: Radiology Source Type: research
Authors: Bolanowski M, Jawiarczyk-Przybyłowska A, Halupczok-Żyła J Abstract Osteoporosis is a systemic disease characterized by bone mass and density loss leading to fragility fractures. Osteoporosis due to endocrine disorders is an example of secondary osteoporosis. The harmful effects on bones are common in patients harboring pituitary tumors (acromegaly, prolactinoma, Cushing's disease) and suffering from hypopituitarism. Increased fracture risk and high healthcare costs of fractured patients are their consequences. The coexistence of some of these disorders and hypogonadism results in severe osteoporosis. Th...
Source: Expert Review of Endocrinology and Metabolism - Category: Endocrinology Tags: Expert Rev Endocrinol Metab Source Type: research
It has been reported that the single nucleotide polymorphism (SNP) rs2854744 at the − 202 locus of insulin-like growth factor binding protein-3 (IGFBP3) is associated with serum levels and a number of malignan...
Source: BMC Medical Genetics - Category: Genetics & Stem Cells Authors: Tags: Research article Source Type: research
Clinical Endocrinology,Volume 0, Issue ja, -Not available-.
Source: Clinical Endocrinology - Category: Endocrinology Authors: Source Type: research
AbstractIntroductionPituitary tumors may have a considerable impact on patients ’ functional status, including paid employment, yet research in this area is sparse.ObjectiveTo describe work disability and its determinants in patients treated for a pituitary tumor.MethodsCross-sectional study including patients treated for a pituitary tumor in the working age (18 –65 years), who completed five validated questionnaires assessing work disability [Short Form-Health and Labour Questionnaire, Work Role Functioning Questionnaire 2.0 (WRFQ)], health-related quality of life (HRQoL) and utility (Short Form-36, ...
Source: Pituitary - Category: Endocrinology Source Type: research
M, Occhi G Abstract CONTEXT: The oral glucose tolerance test (OGTT) is considered the most useful method for diagnosing active acromegaly and for patient follow-up after neurosurgery. Despite its widespread use, only a few small studies have so far focused on patients' clinical features associated with different GH responsiveness to OGTT. OBJECTIVE: We aimed to investigate the association between glucose-induced GH response and endocrine profiles, clinical manifestations, and response to therapy in a large cohort of patients with acromegaly. PATIENTS: Based on GH response to the OGTT, patients were grou...
Source: The Journal of Clinical Endocrinology and Metabolism - Category: Endocrinology Authors: Tags: J Clin Endocrinol Metab Source Type: research
Pituitary adenoma (PA) rarely coexists with Rathke's cleft cyst (RCC). Previously, only 13 cases of patients with growth hormone (GH)-producing PA and concomitant RCC have been reported. Here, the authors report a 54-year-old female patient with a GH-secreting PA coexisting with an RCC. Acromegaly was diagnosed according to the physical examination and endocrine data. Preoperatively, the coronal magnetic resonance imaging (MRI) contained 2 different signal intensities, these unusually MRI findings for the intrasellar mass were rarely. According to our clinical experience for diagnosis of PA and RCC, besides GH-producing PA...
Source: Journal of Craniofacial Surgery - Category: Surgery Tags: Clinical Studies Source Type: research
More News: Acromegaly | Health