Pesticide Exposure and Risk of Rheumatoid Arthritis among Licensed Male Pesticide Applicators in the Agricultural Health Study

Conclusions: Our results provide novel evidence of associations between exposure to some pesticides and RA in male farmers. https://doi.org/10.1289/EHP1013 Received: 24 August 2016 Revised: 19 January 2017 Accepted: 13 February 2017 Published: 14 July 2017 Address correspondence to C.G. Parks, Epidemiology Branch, A3-05, National Institite of Environmental Health Sciences, National Institutes of Health, PO Box 12233, Research Triangle Park, NC 27599 USA; Telephone: (919) 541-2577; Email: Parks1@mail.nih.gov Supplemental Material is available online (https://doi.org/10.1289/EHP1013). The authors declare that they have no actual or potential competing financial interests. Note to readers with disabilities: EHP strives to ensure that all journal content is accessible to all readers. However, some figures and Supplemental Material published in EHP articles may not conform to 508 standards due to the complexity of the information being presented. If you need assistance accessing journal content, please contact ehponline@niehs.nih.gov. Our staff will work with you to assess and meet your accessibility needs within 3 working days. Supplemental Material PDF (210 KB) Note to readers with disabilities: EHP has provided a 508-conformant table of contents summarizing the Supplemental Material for this article (see below) so readers with disabilities may determine whether they wish to access the full, nonconformant Supplemental Ma...
Source: EHP Research - Category: Environmental Health Authors: Tags: Research Source Type: research

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ConclusionsIn this model, compared with IPG SCS or with CMM, Wireless SCS is a superior strategy.
Source: Neuromodulation: Technology at the Neural Interface - Category: Biotechnology Authors: Tags: Clinical Research Source Type: research
Publication date: Available online 17 February 2020Source: Biochimica et Biophysica Acta (BBA) - Molecular Cell ResearchAuthor(s): Ankita Awasthi, Vikrant Nain, Chittur V. Srikanth, Rekha PuriaAbstractLong non coding RNAs (lncRNAs) have emerged as crucial players of several central cellular processes across eukaryotes. Target of Rapamycin (TOR) is a central regulator of myriad of fundamental cellular processes including amino acid transport under diverse environmental conditions. Here we investigated the role of lncRNA in TOR regulated amino acid uptake in S. cerevisiae. Transcription of lncRNA regulates local gene express...
Source: Biochimica et Biophysica Acta (BBA) Molecular Cell Research - Category: Molecular Biology Source Type: research
Org. Biomol. Chem., 2020, Accepted Manuscript DOI: 10.1039/C9OB02765C, Review Articlesaumitra sengupta, G Mehta Abstract: The growing emphasis on macrocycles in engaging difficult therapeutic targets such as protein-protein interactions and GPCRs via preferential adaptation of bioactive and cell penetrating conformations has provided impetus to... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Organic and Biomolecular Chemistry - Category: Molecular Biology Authors: Source Type: research
Notch signaling is a highly conserved intercellular pathway with tightly regulated and pleiotropic roles in normal tissue development and homeostasis. Dysregulated Notch signaling has also been implicated in human disease, including multiple forms of cancer, and represents an emerging therapeutic target. Successful development of such therapeutics requires a detailed understanding of potential on-target toxicities. Here, we identify autosomal dominant mutations of the canonical Notch ligand Jagged1 (or JAG1) as a cause of peripheral nerve disease in 2 unrelated families with the hereditary axonal neuropathy Charcot-Marie-T...
Source: Journal of Clinical Investigation - Category: Biomedical Science Authors: Source Type: research
In this study, a highly CO2-selective two-dimensional (2D) layered metal-organic framework (MOF) showing gate-type adsorption properties was synthesized... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Dalton Trans. latest articles - Category: Chemistry Authors: Source Type: research
Campaign comes as UK prepares an evacuation flight for passengers on the Diamond Princess cruise ship. Follow the latest news and updates hereApple warns of iPhone shortages amid factory shutdownUK trying to contact passengers who left MV WesterdamVirus causes mild disease in four out of five patients, says WHOWhat is coronavirus and what should I do if I have symptoms?Share your experiences7.23amGMTMorning, I ’m Aamna Mohdin taking over the liveblog from Martin Farrer.Britons David Abel and his wife Sally who are on the Diamond Princess cruise ship have tested positive for COVID-19 Coronavirus. Abel, who was been po...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Coronavirus outbreak China Global economy Asia Pacific Business Economics Infectious diseases Science Japan Source Type: news
With far more accidents caused by drugs at the wheel (2016: around 3,200) linked to alcohol-related accidents at the wheel (2016: about 32,700), the issue of drunken driving remains a topical issue. Aspects of this subject are discussed which are currently...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
Adolescence is a key window of vulnerability for depression, the leading cause of disability worldwide. The prevention of depression among young people is therefore of substantial public health importance. A growing body of large-scale data now support...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
BACKGROUND: Unintentional injuries in and around the home are important causes of preventable death and disability among young children globally. In Nepal, there is a lack of data regarding home injuries and home hazards to guide the development of effecti...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Infants and Children Source Type: news
An alcohol interlock device is a breathalyzer with vehicle immobilizer. The road safety effectiveness of alcohol interlocks has been proven in global use, both in the primary preventive and secondary preventive areas. By installing an alcohol interlock, dr...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
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