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Space station project seeks to crystalize the means to counteract nerve poisons

(NIH/National Institute of Neurological Disorders and Stroke) The microgravity conditions of the International Space Station (ISS) may hold the key to improving our understanding of how to combat toxic nerve agents such as sarin and VX. That is the hope of Countermeasures Against Chemical Threats (CounterACT) project that is part of an initiative at the National Institutes of Health aimed at developing improved antidotes for chemical agents.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news

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Discussion With new developments in computational power and data availability, a growing amount of research is using a systems biology approach to understand pathogenesis and progression of disease. Effective and integrated in vitro and in silico models could inform biological phenomena, even without the need of a living subject. For instance, over the last few decades, collagen hydrogel with muscle derived cells (CHMDCs) have promised to revolutionize in vitro experiments and tissue engineering. For CHMDCs to reach the envisioned use, verification by use of mathematical simulations are needed. Recently while examining sha...
Source: PLOS Currents Muscular Dystrophy - Category: Neurology Authors: Source Type: research
INTRODUCTION: Takayasu arteritis (TA) is a rare large vessel arteritis, affecting primarily aorta and its major branches. Its clinical manifestations can vary significantly - from asymptomatic to serious vascular events. Acute neurological complications ar...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Poisoning Source Type: news
Acute global amnesia can occur, due to bilateral hippocampus dysfunction. Causes include the idiopathic syndrome of transient global amnesia, bilateral posterior circulation stroke,. toxic anoxia due to carbon monoxyde poisoning and substance abuse probably combining hypoxia and direct hippocampal neurotoxicity.
Source: Journal of the Neurological Sciences - Category: Neurology Authors: Tags: Letter to the Editor Source Type: research
Conclusions: Our study suggested that incident CHD was positively associated with plasma levels of titanium and arsenic, and inversely associated with selenium. Additional research is needed to confirm these findings in other populations. https://doi.org/10.1289/EHP1521 Received: 22 December 2016 Revised: 17 September 2017 Accepted: 19 September 2017 Published: 19 October 2017 Address correspondence to T. Wu, or A. Pan, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, 13 Hongkong Rd., Wuhan 430030, Hubei, China. Telephone: +86-27-83692347. Email: wut@mails.tjmu.edu.cn or p...
Source: EHP Research - Category: Environmental Health Authors: Tags: Research Source Type: research
Authors: Maher A, Abdel Rahman MF, Gad MZ Abstract Until the beginning of the 1980s, nitric oxide (NO) was just a toxic molecule of a lengthy list of environmental pollutants such as cigarette smoke and smog. In fact, NO had a very bad reputation of being destroyer of ozone, suspected carcinogen and precursor of acid rain. However, by the early 1990s it was well recognized by the medical research community. Over the last two decades, the picture has been totally changed. Diverse lines of evidence have converged to show that this sometime poison is a fundamental player in the everyday business of the human body. NO ...
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
Conclusion: To address the many challenges posed by EDCs, we argue that Africans should take the lead in prioritization and evaluation of environmental hazards, including EDCs. We recommend the institution of education and training programs for chemical users, adoption of the precautionary principle, establishment of biomonitoring programs, and funding of community-based epidemiology and wildlife research programs led and funded by African institutes and private companies. https://doi.org/10.1289/EHP1774 Received: 16 February 2017 Revised: 22 May 2017 Accepted: 24 May 2017 Published: 22 August 2017 Address correspond...
Source: EHP Research - Category: Environmental Health Authors: Tags: Commentary Source Type: research
(NIH/National Institute of Neurological Disorders and Stroke) The microgravity conditions of the International Space Station (ISS) may hold the key to improving our understanding of how to combat toxic nerve agents such as sarin and VX. That is the hope of Countermeasures Against Chemical Threats (CounterACT) project that is part of an initiative at the National Institutes of Health aimed at developing improved antidotes for chemical agents.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
An experimental antiplatelet drug has surprising bite. Based on a protein found in snake venom, the new drug prevented blood clotting in mice without causing excessive bleeding after an injury, according to research published Thursday in the journal Arteriosclerosis, Thrombosis and Vascular Biology. The drug has yet to be tested in humans.Bleeding is a common side effect in the current crop of available antiplatelet drugs, which are usually prescribed for heart patients to prevent blood cells, called platelets, from clumping together and forming clots. Depending on where they occur, clots can lead to a stroke or heart atta...
Source: Medical Hemostat - Category: Medical Devices Authors: Source Type: blogs
View Original Article Here: Nursing Home Signs You May Not Be Noticing As the population ages, more family members find themselves taking care of elderly parents, grandparents or other loved ones. It can be difficult to care for loved ones while working, caring for your children, and keeping up with social commitments. You will likely arrive at a crossroads where you’re forced to ask “when is it time for assisted living?” While many family members do not want to consider committing their loved ones to an institution like an assisted living facility or a nursing home, it isn’t always possible to mov...
Source: Shield My Senior - Category: Geriatrics Authors: Tags: Senior Safety Source Type: blogs
Temperatures were in the 100s when Vanessa Dunn, a 29-year-old Los Angeles-based makeup artist, was driving back home to California from Virginia last summer. After hours on the road and drinking limited water, she was struck by a severe case of dehydration and heat stroke. ”I wasn’t drinking enough water because I didn’t want to stop to pee,” she says. When she finally pulled over for the night she felt light-headed, and she couldn’t keep food down when she tried to eat. She even threw up blood. ”I was in incredible pain, and dizzy,” she says. “[I went] to the ER, turned out...
Source: Science - The Huffington Post - Category: Science Source Type: news
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