Mathematical Simulation of Transport Kinetics of Tumor-Imaging Radiopharmaceutical (99m)Tc-MIBI.

Mathematical Simulation of Transport Kinetics of Tumor-Imaging Radiopharmaceutical (99m)Tc-MIBI. Comput Math Methods Med. 2017;2017:2414878 Authors: Shevtsova ON, Shevtsova VK Abstract The proposed model describes in a quality way the process of tumor-imaging radiopharmaceutical (99m)Tc-MIBI distribution with taking into account radiopharmaceutical accumulation, elimination, and radioactive decay. The dependencies of concentration versus the time are analyzed. The model can be easily tested by the concentration data of the radioactive pharmaceuticals in the blood measured at early time point and late time point of the scanning, and the obtained data can be used for determination of the washout rate coefficient which is one of the existing oncology diagnostics methods. PMID: 28702073 [PubMed - in process]
Source: Computational and Mathematical Methods in Medicine - Category: Statistics Tags: Comput Math Methods Med Source Type: research