Psychotherapy Alone and Combined With Medication as Treatments for Bipolar II Depression: A Randomized Controlled Trial.

CONCLUSIONS: IPSRT plus quetiapine resulted in greater symptomatic improvement but also more side effects than IPSRT alone. A subset of participants improved with IPSRT alone, although absence of an inactive comparator limits interpretation of this finding. Receipt of preferred treatment was associated with better outcomes. Harms, benefits, and preferences should be considered when recommending treatments for BP-II depression. TRIAL REGISTRATION: ClinicalTrials.gov identifier: NCT01133821. PMID: 28703949 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/28703949?dopt=Abstract

Source: Journal of Clinical Psychiatry - July 15, 2017 Category: Psychiatry Tags: J Clin Psychiatry Source Type: research