Subcortical Surface Shape in Youth at Familial High Risk for Schizophrenia

Schizophrenia is an incapacitating disorder: the effects of cognitive deficits (e.g. impaired attention, memory), positive symptoms (e.g. delusions, hallucinations), and negative symptoms (e.g. social withdrawal) (Keshavan et al., 2011) may lead to severe functional disability. First-degree relatives of individuals with schizophrenia, including offspring, dizygotic twins and full siblings, are at familial high risk for developing schizophrenia (HRSZ) and have about a 10% chance of developing the disorder (Gottesman, 1991).

Source: Psychiatry Research: Neuroimaging - July 14, 2017 Category: Psychiatry Authors: Kathryn Hill, Nicolas Bolo, Suraj Sarvode Mothi, Paulo Lizano, Synthia Guimond, Neeraj Tandon, Elena Molokotos, Matcheri Keshavan Source Type: research